Mass Transport Flashcards
What is haemoglobin?
A protein with a quaternary structure with a haem group contain iron ions that carries 4 oxygen molecules in the blood
What is loading in haemoglobin?
Haemoglobin binding to oxygen in the lungs
What is unloading in haemoglobin?
Haemoglobin releasing oxygen (at respiring tissues)
How does affinity affect loading and unloading?
Haemoglobin with a high affinity loads easier whereas haemoglobin with a low affinity unloads easier
What are some needed features in a double circulatory system?
- medium to carry materials (e.g. blood)
- form of transport (e.g blood vessels)
- method of moving medium (e.g. heart)
Where does the pulmonary artery go to and from?
Goes to lungs from right ventricle
Where does the pulmonary vein go to and from?
Goes to the left atrium from the lungs
Where does the aorta go to and from?
Goes to the body from the left ventricle
Where does the vena cava go to and from?
Goes to the right atrium from the body
Where does the renal artery go to and from?
Goes to the kidney from the aorta
Where does the renal vein go to and from?
Goes to the vena cava from the kidney
What does an oxygen dissociation curve show?
The saturation of haemoglobin with oxygen at different partial pressures of oxygen
Why is an oxygen dissociation curve S shaped?
- the first oxygen binds to the haemoglobin which changes the tertiary structure of the haemoglobin
- making it easier for the 2nd and 3rd oxygen to bind
- it is harder for the 4th to bind due to probability
- positive cooperativity
What is the effect of increased carbon dioxide on the oxygen dissociation curve?
- curve shifts to the right
- carbon dioxide reduces pH of blood
- alters tertiary structure of haemoglobin
- more unloading of oxygen at the respiring tissues
- Bohr shift
What are the 4 chambers of the heart?
Left atrium, left ventricle, right atrium, right ventricle
What are the 4 blood vessels at the heart?
Vena cava, pulmonary artery, pulmonary vein, aorta
What are the valves in the heart?
Atrioventricular valve and semilunar valve
What holds valves in place?
Tendons
What is the role of the septum?
Prevents oxygenated and deoxygenated blood mixing
What is the role of valves?
Prevent back flow of blood so they are unidirectional
How do valves maintain unidirectional flow?
- open when pressure behind is greater than pressure infront
- close when pressure infront is greater than pressure behind
What is the role of coronary arteries?
External arteries that supply cardiac muscle with oxygen and remove waste products