MASS STUDY QUESTIONS Flashcards
What are the three lines of defence against changes in pH
- Buffers
- Respiratory System
- Kidney’s and H+
What do buffers do?
A buffer is a molecule that moderates, but does not prevent changes in pH by combining with or releasing ions.
How does the Kidney control pH?
H+ excretion
HCO3- excretion
ammonia secretion
How does the kidney respond to acidosis?
Kidney will increase H+ secretion and increase excretion and urine and increase bicarbonate reabsorption.
How does the kidney respond to alkalosis?
kidney will excrete bicarbonate and converse more hydrogen
What is the function of vasopressin?
It controls water reabsorption. It causes diuresis which is the elimination of water and does this by increasing the number of aquaporins.
What is the function of renin?
is a hormone that controls blood pressure.
What is the function of angiotensin II?
stimulates the release of aldosterone from the adrenal cortex
What is the function of aldosterone?
promotes sodium reabsorption in the kidney
What is the function of the Atrial Natriuretic peptide (ANP)?
inhibits Na reabsorption in the distal tubule.
What are the 3 forces that drive glomerular filtration?
- glomerular capillary blood (hydrostatic pressure)
- Plasma Colloid Osmotic Pressure
- Bowman’s Capsule Hydrostatic Pressure
What are the 3 barriers that glomerular filtration must pass through?
- Glomerular Capillary Epithelium
- Basal lamina
- Epithelium of bowman’s capsule
Specificity
the ability of an enzyme or receptor molecule or a group of closely related molecules
Saturation
All active sites on a given amount of protein are filled with substrates and the reaction rate is maximal
Competition
A transporter may move several membranes of a related group of substrates, but those substrates compete with one another for binding sites on the transporter