Markers/Staining Flashcards

1
Q

Vimentin

A

Connective Tissue

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2
Q

Desmin

A

Muscle

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3
Q

Cytokeratin

A

Epithelial Cells

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4
Q

GFAP

A

Neuroglia

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5
Q

Neurofilament

A

Neurons

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6
Q

Giemsa

A

Chlamydia, Borrelia, Rickettsiae, Trypanosomes, Plasmodium

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7
Q

PAS

A
gylcogen, mucopolysaccharides
Whipple Disease (Tropheryma whipplei)
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8
Q

Ziehl-Neelsen

A

Acid-Fast

Nocardia, Mycobacterium

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9
Q

India Ink

A

Cyrptococcus neoformans

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10
Q

Silver (Grocott) Stain

A

Fungi, Leigonella, H. pylori

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11
Q

ALP

A

metastasis to bone, liver, Paget disease of bone, seminoma

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12
Q

alpha-Fetoprotein

A

hepatocellular carcinoma, hepatoblastoma, yolk sac tumor, testicular cancer, mixed germ cell tumor

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13
Q

beta-hCG

A

hydatidiform moles, choriocarcinomas, testicular cancer

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14
Q

CA-15-3/CA-27-29

A

breast cancer

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15
Q

CA-19-9

A

Pancreatic adenocarcinoma

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16
Q

CA-125

A

ovarian cancer

17
Q

calcitonin

A

medullary thyroid carcinoma

18
Q

carcinoembryonic antigen (CEA)

A

nonspecific

colorectal, pancreatic, gastric, breast, medullary thyroid

19
Q

PSA

A

follow prostate adenocarcinoma, BPH and prostatitis

20
Q

S-100

A

neural crest origin

melanoma, schwannomas, Langerhans cell histiocytosis

21
Q

TRAP

A

tartrate-resistant acid phosphatase

hairy cell leukemia (B cell)

22
Q

CEA

A

marker for colorectal cancer

monitoring, not screening