Markers Flashcards by Karina Katchko

Q

All T Cells

A

CD3

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Q

Helper T Cells

A

CD4

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Q

Cytotoxic T Cells

A

CD8

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Q

Granulocytes, Monocytes

A

CD13

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Q

B Cells (not plasma cells)

A

CD19 & CD20

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Q

Blasts/Stem Cells

A

CD34

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Q

Leukocytes

A

CD45 (aka LCA)

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Q

Flow cytometry Tcells

A

CD45

CD3

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Q

Flow cytometry granulocytes

A

CD45

CD15

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Q

Markers seen in AML

A

MPO

NSE

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Q

Markers of Immaturity

A

CD34

CD117

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Q

Myeloid

A

CD13
CD15
CD33
MPO

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Q

New prognostic markers in AML & prognosis

A

FLT3-poor

NPM1-favorable unless with FLT3

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Q

Langerhans cell histocytosis

A

CD1a, langerin

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Q

CD3

A

thymocytes, mature Tcells

always in TALL

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Q

CD5

A

T cells, mantle cell lymphoma, CLL/SLL

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Q

Mantle Cell Lymphoma

A

CD5, FMC7, CD19, CD20, surface Ig

Q

CLL/SLL

A

CD5, CD23, CD19, CD20

Q

CD10

A

preBcells and germinal center Bcells

Q

CD21

A

EBV receptor
mature B cells
Follicular dendritic cells

Q

CD11c & CD22

A

Hairy Cell leukemias

Q

CD15

A

Reed-Sternberg cells

Q

CD30

A

Reed-Sternberg cells

Q

B-ALL

A

CD19

CD10

T-ALL

CD1 CD2 CD5 CD7

blood smear finding for CLL/SLL

smudge cells

What is bence jones protein?

free light chains in the urine | seen in multiple myeloma w/kidney disease

M spike

MGUS Multiple Myeloma Amyloidosis

AML

``` CD13 CD14 CD15 CD33 CD117 ```

ALL

CD3 CD19 CD20

What is the pre leukemia for AML? ALL?

AML:myelodysplasia ALL:none

T-ALL flow cytometry

CD3 | CD1a

Follicular Lymphoma

CD10 (CD5-)

MALT Lymphoma

CD10- | CD5-

TRAP+

Hairy Cell

ATLL

CD4+

Follicular Lymphoma

CD19, CD20, CD10

Burkitt's lymphoma

``` IgM CD19 CD20 CD10 BCL6 ```

Hodgkin Lymphoma

CD15 CD30 FAIL to express CD45

Lymphocyte Predominance Hodgkin Lymphoma

CD20 | FAIL to express CD15 and CD30