Intro to Bone Marrow Transplant Flashcards
1
Q
What creates the difference in histoincompatabiliy between identical twins/self and an HLA matched sibling?
A
minor histocompatibility agents don’t match
2
Q
What can hematopoeitic cell transplant be used for?
A
CML, AML, ALL
sickle cell
thalassemia
SCID
3
Q
Can bone marrow transplants cure hemophilia?
A
NO
4
Q
What is the most problematic side effect of peripheral blood progenitor cell transplant?
A
chronic Graft vs Host Disease
5
Q
What significant endocrinologic side effect can radiation cause?
A
hypothyroidism
6
Q
When can you use autotransplant?
A
for cancers that start outside the bone marrow
7
Q
What beneficial effect can graft vs host disease have?
A
can kill off cancer cells (graft vs tumor)
