March 14

Question 1

Purpose of animal use (6)

Answer 1

1. Breeding colony
2. Studies of a fundamental nature in science relating to essential structure or function
3. Studies for medical purposes (including vet med)
4. Studies for regulatory testing
5. Studies for the development of products or appliance for human or veterinary medicine
6. Education & training

Question 2

Regulations around animal use in science

Answer 2

Not regulated or monitored
- Federal government does not regulate
- CFIA has conditions for animal handling
- Health of Animals Act mainly protects livestock
- Criminal Code of Canada against cruelty

Question 3

Examples of provincial regulation

Answer 3

• Animals for Research Act in Ontario (1970)
• Chief Veterinary Inspector, OMAFRA
• Research facilities & supply facilities

Question 4

How institutional level animal welfare is regulated

Answer 4

• University of Guelph Animal Care Policy
• Animal Care Committees (ACCs)

Question 5

When is animal use reported?

Answer 5

• Use of vertebrates (alive and deliberately euthanized for use)
• Use of cephalopods

Question 6

AUP

Answer 6

Animal Utilization Protocol
(focus on sections personnel, animals, experiments/endpoint, procedures)

Question 7

Categories of invasiveness (5)

Answer 7

A. Most invertebrates or live isolates
B. Little or no discomfort or stress
C. Minor stress or pain of short duration
D. **Moderate to severe distress of discomfort
E. **Severe pain near, at, or above the pain tolerance threshold of unaesthetized conscious animals

Question 8

Categories of Welfare Impact (5)

Answer 8

A. Positive (improved welfare)
B. Mild negative (low severity/duration)
C. Moderate negative (low-medium)
D. High negative (medium-high)
E. Severe negative

Requires understanding of how animals experience the world in which they live

Question 9

3Rs

Answer 9

Replacement
Reduction
Refinement

Question 10

Replacement (3Rs)

Answer 10

Methods which avoid or replace the use of animals

Question 11

Reduction (3Rs)

Answer 11

Strategies that will result in fewer animals being used

Question 12

Refinement (3Rs)

Answer 12

Modifications of husbandry or experimental procedures to minimize pain & distress & enhance welfare of animals used

Question 13

Key area for animal care council @UOG (5)

Answer 13

1. 3Rs
2. Invasive studies
3. Early endpoints & pilot study
4. Environmental enrichments
5. Scientific merit vs. ethical review