Mania

Question 1

What is Mania

Answer 1

A term to describe a state of feeling or mood, that can range from near-normal experience to severe, life-threatening illness. Pathological, inappropriate elevated mood.

Question 2

What is mania often associated with

Answer 2

Grandiose ides, disinhibition, loss of judgement, similar to effects of stimulant drugs

Question 3

Hypomania

Answer 3

Lesser degree of mania, no psychosis. Theres a mild elevation of mood for severeal days on end. Increased energy and activity, marked feeling of wellbeing . Increased sociability, talkativeness, overfamiliarity, sexual energy. The patient may be irritable. Mild overspending

Question 4

Mania

Answer 4

1 week, severe enough to disrupt ordinary work and social activities more or less completely. The patient will have elevated mood, increased energy, overactivity, pressure of speech, decreased need for sleep.
Disinhibition, 
alteration of senses, ]
grandiosity 
Extravagant spending

Question 5

Differential diagnosis of mania (psychiatric)

Answer 5

Mixed affective state
	Schizoaffective disorder
	Schizophrenia
	Cyclothymia
	ADHD
	Drugs and Alcohol

Question 6

Differential diagnosis of mania (medical)

Answer 6

Stroke, MS, Tumour, epilepsy, AIDS, Neurosyphilis
Endocrine – Cushing’s, hyperthyroidism
SLE

Question 7

Tools to measure symptoms of mania

Answer 7

SCID, SCAN, Young Mania Rating Scale

Question 8

Antipsychotic treatment of mania

Answer 8

Olanzapine
Risperidone
Quetiapine

Question 9

Mood stabiliser treatment of mania

Answer 9

Sodium Valproate
Lamotrigene
Carbamazepine

Question 10

Other treatments of mania1

Answer 10

Lithium, ECT

Question 11

Bipolar Affective Disorder

Answer 11

Repeated episodes of depression and mania.

Question 12

Epidemiology of bipolar disorder

Answer 12

More common in females, at the age of onset being 21, usually there is positive family history,

Question 13

Lifetime prevelance of bipolar

Answer 13

0.7-1.6/100

Question 14

Lifetime prevelance rate of depression

Answer 14

2.9-12

Question 15

Lifetime risk for less severe manifestations of depression

Answer 15

20

Question 16

Female to Male ratio of depression

Answer 16

2:1

Question 17

Highest risk of depression

Answer 17

18-44

Question 18

Clinical course of major depression

Answer 18

Typical episode lasts 4-6 months, 54% recovered at 26 weeks, 12% fail to recover, 80% have further episodes, 15% die by suicide

Question 19

Clinical course of bipolar disorder

Answer 19

Typical episode lasts 1-3 months, 60% recovered at 10 weeks, 5% fail to recover, 90% have further episodes, 1.3 have a poor outcome, 10% die by suicide