Anxiolytics

Question 1

What are anxiolytics used to treat

Answer 1

panic disorder, generalized Anxiety disorder, substance-related disorders and their withdrawal, insomnias and parasomnias. In anxiety disorders often use anxiolytics in combination with SSRIS or SNRIs for treatment.

Question 2

Pros of buspirone

Answer 2

Good augmentation strategy- Mechanism of action is 5HT1A agonist. It works independent of endogenous release of serotonin.
No sedation

Question 3

Cons of Buspirone

Answer 3

Takes around 2 weeks before patients notice results.
Will not reduce anxiety in patients that are used to taking BZDs because there is no sedation effect to “take the edge off.

Question 4

Benzodiazapines are use to treat

Answer 4

Insomnia, parasomnias and anxiety disorders

Question 5

Side effects of benzodiazapines

Answer 5

Somnolence
Cognitive deficits
Amnesia
Disinhibition
Tolerance
Dependence

Question 6

Examples of benzodiazapines

Answer 6

Alprazolam, chlordiazepoxide, diazepam