Malignant Tumors

Question 1

Malignant tumors in children (2)

Answer 1

Osteosarcoma

Ewings sarcoma

Question 2

Malignant tumors in 20-50 (5)

Answer 2

Lymphoma
Osteomyletis
Chondrosarcoma
Parosteal osteosarcoma
PUS (pleomorphic undiferentiated sarcoma)

Question 3

Malignant tumors in 40-70 (2)

Answer 3

Matastisis

Multiple myeloma

Question 4

Osteosarcoma- age, pain, location, border/matrix/soft tis, prog

Answer 4

age-15-24

pain- insideous, intermittent pain+swell

loc- cortex + medulllary cavity of long bone (central mc)

Imaging
- lucid but could be unorganized sclerotic, ill defined margins w cortical destruction.
-Soft tissue mass (cumolus cloud), laminated/spiculated pareosteal
Prog- risk of metastiss

Question 5

Pareosteal osteosarcoma- age, loc, pain, matrix/boder

Answer 5

30-40

Loc- metaphysis (cortex)

Pain- dull, intermittent pain

Imaging- extraossseous mass connected to parent bone by stalk, Scelrotic (in middle)

Question 6

Chondrosarcoma- age, pain, loc, border/matrix

Answer 6

age- 40-60
Pain- dull, aching + some swelling
loc- metaphysis of long bone/pelvis/spine

Imaging- ill defined lucent w/ calcifications (rings + arcs), maybe some pareosteal rxn

Question 7

Pleomorphic Undifferentiated sarcoms (PUS)- age, pain, border/matrix

Answer 7

Age- 30-50

pain- Pain and alot of swelling compared to others

imaging- lytic lesion w poorly definied margins, expansile and detroys cortex. Pareosteal rxn rare

Question 8

What is the most common primary bone tumor

Answer 8

multiple myeloma

Question 9

What will someone with multiple myeloma present with clinically

Answer 9

anemia (fatigue)
Mechanical pain (mproves w rest)
Renal disease

Question 10

Multiple myeloma- age, loc, Imaging findings (normal, spine, skull)

Answer 10

Age- 50-70

Loc- diaphysis of long bone, bery body (ant), can be multiples

Imaging- punched out lytic lesions to osteopendia
(in spine will appear as collapsed vert, skull will have punched out lesions)

Question 11

What are lab tests for myeloma (3)

Answer 11

1. CBC(plasma cell proliferation)= will have anemic pres
2. Urinalysis= bence jones protenurea
3. Immunoelectrophoresis- Looking for m spike elevations

Question 12

Ewings sarcoma- age, pain, loc, border/matrix/rxn

Answer 12

Age- 10-25

pain- local pain + soft tissue mass

location- diaphyseal (kinda on cortex)

Imaging- ill defined margins w. lucent permiative destruction w/ cortical saucerization
-laminated pareosteal rxn

Question 13

What is mc tumor to mets to another location

Answer 13

Ewings sarcoma