Malignant bone tumours

Question 1

what group of people do osteosarcomas occur in

Answer 1

young adults 60% are under 25
older patients have predisposing factors
M>F

Question 2

what is produced in osteosarcoma

Answer 2

malignant osteoclasts form osteoid

Question 3

where does osteosarcoma occur

Answer 3

at the end of long bones

Question 4

what does osteosarcoma present like

Answer 4

grows out of bone, raising bony capsule - runs over the surface
erodes and destroys bony cortex and extends into soft tissue

Question 5

codmans triangle

Answer 5

raised triangle on x-ray

Question 6

what are the variants of osteosarcoma

Answer 6

osteoblastic, chordoblastic, fibroblastic

Question 7

what are the investigations for osteosarcoma and the treatment

Answer 7

biopsy, CT for mets
pre op chemo
surgical resection
post op chemo

Question 8

large and slow to metastasis

Answer 8

chondrosarcoma

Question 9

malignant nodules - finger like processes infiltrate lamellar bone obliterating marrow - separation of nodules by fibrous bands

Answer 9

chondrosarcoma

Question 10

exhibits pure hyaline differentiation

Answer 10

chondrosarcoma

Question 11

Who does ewings sarcoma occur in

Answer 11

10-20s

Question 12

malignant primary bone tumour of the endothelial cells of the marrow

Answer 12

ewings sarcoma

Question 13

what is the presentation of ewings sarcoma

Answer 13

great mimic - hot swollen tender joint w raised inflame markers

Question 14

red brown tumour mass breaking through cortex

Answer 14

ewings sarcoma