Male Reproductive Histology Flashcards
what structure produces sperm, synthesizes and secretes androgens
testes
what structures form the educt system that transports sperm
epididymus, vas deferens, ejaculatory duct, urethra
what structures contribute fluid secretions to semen and provide nutrients to ejaculated sperm
accessory glands (seminal vesicles, prostate gland, bulbourethral glands)
the testis are enclosed in the ______ _____ that thickens to form the ________ where the rete testis are located
enclosed in the tunica albuginea
thickens to form the mediastinum
a network of spaces contained within the CT of the mediastinum that exists between the tubulus rectus and the ductuli efferentes
rete testis
the seminiferous tubules consist of a central lumen lined by a specilized seminiferous epithelium made up of
somatic sertoli cells and sspermatogenic cells
epithelium is surrounded by a lamina propria (multilayered CT, collagen , 3-5 layers of myoid cells)
leydig cells found between seminiferous tubules
somatic columnar sertoli cells interact with what three cell types
spermatogonia (mitotic)
spermatocytes (meiotic)
spermatids (haploid, undergoing spermiogenesis)
the seminiferous epithelium houses what types of nuclei (4)
nuclei of spermatogonia and sertoli cells (closely associated with tubular walls)
spermatogonial cells - larger nuclei and clumps of chromatin
early spermatids
late spermatids
functions of sertoli cells
support, protect, and nourish developing spermatogenic cells
eliminate residual bodies via phagocytosis (discarded by spermatids during spermiogenesis)
release of mature spermatids into lumen of tubule (spermiation)
at the basolateral domain, sertoli cells have tight junctions that create basal and adluminal compartments
the basal compartment houses spermatogonial cells in ______, allowing greater acces to nutrients and signaling molecules
the adluminal compartments establish a ____-_____ barrier that protects developing spermatopcytes and spermatids from autoimmune reactions
niches
blood-testes barrier
where can leydig cells be found
in the intertubular space
close to blood vessels and lymphatic channels
they are steroid producing cells so they contain lipid droplets, mitchondria with tubualr cristae and well devloped sER
diploid cells that reside in a niche of basal compartments of sertoli cells
spermatogonia
difference between type A and type B spermatogonia
type a: oval, euchromatic nucleus and nucleolus attached to the nuclear envelope
type b: round nucleus, masses of heterochromatin attached to nuclear envelope and central nucleolus