Male Reproductive Histology Flashcards
Sertoli cells respond to what?
FSH
What forms the blood-testis barrier?
Tight junctions between Sertoli cells
What is the purpose of the blood-testis Barrier?
To keep the developing sperm isolated from the immune system because they will be recognized as NON self
Disorder where the seminiferous tubule has only Sertoli cells and no Spermatogonia - infertile. And the Leydig cells have Reinke Crysalloids which are also seen in Leydig cell tumors.
Sertoli Cell only syndrome (SCOS)
Primary Spermatocytes are _______ for chromosome number but ________ for DNA
Diploid; tetraploid
Secondary Spermatocytes are _______ for chromosome number and ________ for DNA
Haploid; diploid
Spermatids are ________ for both chromosome number and DNA
Haploid
What are the 4 major events of Spermiogenesis?
- Development of the flagellum
- Development of the Acrosome
- Development of the manchette
- Nuclear condensation (protamines)
In the development of the sperm, what is the band of microtubules called that helps collapse down the nucleus and change it’s shape?
Manchette
No dynein arms. Flagella can’t beat properly so sperm can’t swim correctly
Primary ciliary Dyskinesia or Immotile Cilia Syndrome or Kartagener’s Syndrome
Oligospermia or hypos permit can be caused by deletion of what?
AZF region on Y chromosome
Leydig cells respond to what?
LH
Dilation of veins in spermatic cord causing a decrease in sperm production
Varicocele
Mumps is associated with what clinical consideration of the testes.
Acute orchitis - infection that spreads to testes
These produce and alkaline viscous fluid, rich in fructose used for ATP, fluid also contains citrate, prostaglandins, and several proteins necessary for coagulation of semen.
Seminal vesicles
