Male Reproductive

Question 1

the testes produce ___

Answer 1

sperm

Question 2

the testes secrete which hormones

Answer 2

testosterone, estradiol, AMH, inhibin B

Question 3

the enzyme ______ converts testosterone to dihydrotestosterone

Answer 3

5 alpha reductase

Question 4

testosterone is produced by the _____ cells of the testes

Answer 4

leydig

Question 5

functions of testosterone

Answer 5

hair growth, sperm production, erectile function, prostate growth, muscle growth, increased sex drive, improved mood, confidence, memory function, maintenance of bone mass density

Question 6

mechanism of action of testosterone

Answer 6

activated by 5 alpha reductase, binds to androgen receptor, goes to nucleus

Question 7

role of estrogen in males

Answer 7

sperm health, combating osteoporosis, heart health

Question 8

80% of the estradiol and 95% of the estrone in plasma are not directly from testes, but from _____

Answer 8

aromatase expressing organs

Question 9

a small amount of estrogens are produced in the testes from the ___ and ___ cells

Answer 9

leydig, sertoli

Question 10

AMH is produced by the ____ cells of the testes

Answer 10

sertoli

Question 11

AMH expression is critical to ________ at a specific time during fetal development, which inhibits ______

Answer 11

sex differentiation, the development of the female reproductive tract in the male embryo

Question 12

inhibin B is secreted from ___ cells of testes

Answer 12

sertoli

Question 13

_____ stimulate inhibin production

Answer 13

androgens

Question 14

inhibin b is a marker of _____

Answer 14

male infertility

Question 15

serum inhibin b is significantly _____ in fertile men than infertile men

Answer 15

higher

Question 16

inhibin b inhibits ____

Answer 16

FSH

Question 17

androgen receptor inhibitors for treatment of prostate cancer

Answer 17

apalutamide, darolutamide, enzalutamide

Question 18

CYP17 inhibitor for prostate cancer treatment

Answer 18

abiraterone acetate