Male breast cancer Flashcards
1
Q
Usual positive IHC stain
A
ER
2
Q
Male breast cancer is strongly associated with BRCA2 (BRCA2 mutations will be present in 60% to 76% of families with a male having breast cancer); ____ mutations are less frequently associated
A
BRCA1
3
Q
T/F. Presents at higher stage
A
True; because of the scant amount of male breast tissue, carcinomas tend to invade skin and chest wall earlier and present at higher stages
4
Q
T/F. Same survival rate as women stage by stage
A
True
5
Q
Risk factors
A
- Radiation
- Estrogen therapy
- Testicular feminizing syndromes
6
Q
Treatment
A
MRM + chemo + RT + endocrine therapy
