Atypical ductal hyperplasia (ADH)

Question 1

Atypical ductal hyperplasia shares some morphologic features with ductal carcinoma in situ (DCIS) but ____

Answer 1

Is limited in extent

Question 2

Histopath finding

Answer 2

• Nests of monomorphic cells, and ducts filled with the same cells, showing cribriform “cookie-cutter” pattern
• Changes do not involve the whole duct

Question 3

How is it different to DCIS?

Answer 3

• ADH
  
  • Changes do not involve the whole duct
• DCIS
  
  • Full duct involvement

Question 4

How is it different to epithelial hyperplasia?

Answer 4

• ADH
  
  • Nests of monomorphic cells, and ducts filled with the same cells, showing cribriform “cookie-cutter” pattern
• Epithelial hyperplasia
  
  • Heterogenous