Male and female physiology Flashcards

1
Q

what cells produce sperm?

A

germ cells

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2
Q

what cells produce testosterone?

A

interstitial / leydig cells

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3
Q

what cells produce inhibin/ mullein inhibiting hormone MIH?

A

sertoli cells

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4
Q

what hormone triggers spermatogenesis?

A

FSH

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5
Q

what hormone triggers development of male sex characteristics?

A

LH - leydig cells - androgens (testosterone)

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6
Q

where is mature sperm located?

A

epididymis

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7
Q

what are the 2 phases of the ovarian cycle and what hormones dominate?

A

follicular stage: FSH

luteal stage: LH

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8
Q

what are the phases of the menstrual cycle and what hormones dominate?

A

proliferative phase - oestrogen

secretory phase - progesterone

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9
Q

what hormone is responsible for stopping the menstrual cycle during pregnancy and how?

A

human chorionic gonadotrophin (HCG)
increase of progesterone acts on the corpus luteum to stop it from developing into corpus albicans and therefore keep producing progesterone

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10
Q

what is the role of progesterone?

A

makes the uterine lining thicker, more vascular and secretory in order to make it a suitable environment for implantation

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11
Q

what produces progesterone?

A

corpus luteum

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12
Q

peak of what hormone triggers ovulation?

A

LH

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13
Q

briefly describe oogenesis in females.

A

oogonium undergo mitotic division to produce primary oocytes before or shortly after birth.
due to the influence of hormones, during each cycle, after puberty, one of the primary oocyte dominate and undergo first meiotic division to release secondary oocyte at ovulation
if fertilisation occurs, secondary oocytes undergo second meiotic division to produce mature ovum

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14
Q

give an example of a central cause which affects oogenesis.

A

pituitary/hypothalamic tumour,

functional i.e. excessive exercise, low/high BMI, stress

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15
Q

give an example of a peripheral cause which affects oogenesis.

A

turners syndrome

pre mature ovarian failure: FSH and LH are high but oestrogen is very low

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16
Q

give an example of a peripheral cause which affects spermatogenesis.

A

secondary to vasectomy

kleinfelters syndrome - testicular failure

17
Q

what is the dominant factor which affects female fertility and why?

A

age due to natural decline in ovarian reserve

18
Q

what is the role of sertoli cells?

A

produces mullerin inhibiting hormone and supports germ cells in spermatogenesis