Embryology Flashcards

1
Q

what is the embryological origin of the gonads?

A

mesonephros

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2
Q

what is the median umbilical ligament a remnant of?

A

allantois

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3
Q

what does the gonadal ridge form from?

A

the mesonephros

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4
Q

what is Wollfian duct and Mullerian duct?

A

wollfian duct = mesonephric duct

Mullerian duct = paramesonephric duct

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5
Q

does the paramesonephric duct disappear in males or females?

A

males

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6
Q

does the mesonephric duct disappear in males or females?

A

females

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7
Q

in females, what forms the fallopian tubes, vagina, cervix and uterus?

A

paramesonephric duct

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8
Q

in males, what forms the vas deferent, epididymis and seminal vesical?

A

mesonephric duct

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9
Q

what forms the testes and ovaries?

A

undifferent gonad

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10
Q

from what structure does the prostate develop from?

A

urogenital sinus

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11
Q

from what structure does the lower part of the vagina develop from?

A

urogenital sinus

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12
Q

how does the indifferent gonads decide it will develop into testes?

A

SRY on the Y chromosome codes for a protein called testes determining factor (TDF) which makes them develop into testes
also causes production of sertoli cells and leydig cells which cause release of testosterone and therefore male sex characteristics

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13
Q

how does the indifferent gonad develop into ovaries?

A

there is no SYR region and no TDF and by default the ovaries develop

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14
Q

mesonephric duct degenerates in male or female?

A

female

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15
Q

paramesonephric duct degenerates in male or female?

A

male

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16
Q

what is responsible for the gonads descending down from lumbar region to pelvic?

A

Gubunaculum

17
Q

what does the gabernaculum form in the female?

A

once the ovaries have reached the pelvis the gabernaculum forms the ovarian ligament

18
Q

why are females less likely to have indirect inguinal hernias?

A

the ovaries don’t descend through the inguinal canal and therefore the canal is smaller in females therefore less prone

19
Q

when are the testes fully descended?

A

8 months

20
Q

what is cryptochordism?

A

absence of testes in scrotum

21
Q

what are the complications of undescended testes?

A

infertillity
malignant transformation (germ cell tumours)
testicular torsion

22
Q

what is the management for cryptochordism?

A

orchiopexy

23
Q

at what weeks is there greatest risk of complications from teratogens?

A

1st trimester weeks 3-11

24
Q

what complications occur due to exposure from teratogens in the 3rd trimester?

A

growth and/or functional deficits

25
Q

where does the lower part of the vagina and the vulva develop from?

A

urogenital sinus

26
Q

what are the clinical features of foetal alcohol syndrome?

A
low nasal bridge 
underdeveloped lower jaw 
thin upper lip
smooth and large philtrum 
small head 
small eye opening 
flat mid face 
epicanthal folds
27
Q

what is the triad of complications from catching rubella in pregnancy?

A

sensorineural deafness
microphalmia, cataract and retinopathy
congenital heart disease: pulmonary artery stenosis, patent ductus arteriosus

28
Q

what complications/effects can a vaginal septum have?

A
a/dyspareunia 
miscarriage
infertility 
abnormal lie in pregnancy
abnormal labour 
heavy periods
no effect
29
Q

what complications can the use of/over use of opiates have on the foetus?

A

respiratory depression which can effect the brain and skeleton

30
Q

what is the embryological origin of the indifferent gonads?

A

intermediate mesoderm

31
Q

what is the embryological origin of the bladder?

A

urogenital sinus

32
Q

what is the embryological origin of the urethra?

A

urogenital sinus