malaria Flashcards

1
Q

when do malaria symptoms that include fever, chills and sweating start?

A

malaria parasite initially enters liver where it replicates. the parasites are then released into circulation and enter RBC where they proliferate and cause the blood cells to rupture. **symptoms coincide with the rupture of the RBC

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2
Q

release of Plasmodium ……….. parasite from ruptured RBC occurs every 48 hrs
which causes fever to occur every …………..?

A

vivax

48hrs

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3
Q

………… may be present in patient w malaria. could be due to ruptured RBC, inflammation of the liver caused by parasite, or consequence of using anti-malarial medication

A

jaundice

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4
Q

………….. blood smear is examined for the presence of malaria parasite

A

thick

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5
Q

with which type of plasmodium parasite may relapse malaria due to the presence of dormant forms of the parasite in the liver?

A

P. vivax and P. ovale

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6
Q

The mosquito , called …………, carries the parasite

……………, which transmits the disease ………….

A

Anopheles
plasmodium
Malaria

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7
Q

Plasmodium …………., which normally infects macaques(type of monkeys), is known to
cause zoonotic malaria in Southeast Asia

A

knowlesi

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8
Q

there’s a correlation b/w malaria and ….?

A

poverty

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9
Q

plasmodium vivax requires special antigen on the RBC called ………….. in order to infect the RBC. those who have …………. disease lack this antigen so they are protected from malaria

A

duffy antigen

sickel cell anemia

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10
Q

while the plasmodium parasite is in the mosquito, it’s in the stage known as …………..
when the plasmodium parasite is transmitted into the blood circulation then to the liver, they multiply asexually and turn into …………..

A

sporozoite

merozoites

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11
Q

which type of plasmodium can go dormant in the liver? and what do they become called as? and phase are they in?

A
P. ovale and P.vivax
Hypnozoites (don't divide)
Exoerythrocytic phase (bcz they are not in RBC)
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12
Q

which merozoite(plasmodium in liver)invade which of the following RBC:

1) RBC of all ages:
2) Reticulocytes(young RBC):
3) older RBC:

A

1) P.ovale and P.falciparum
2) P.vivax
3) P.malariae and P.knowlesi

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13
Q
Continuous cycling or delayed multiplication in the liver (hypnosoites) may cause periodic relapse over
several years (1–2 years in P. ovale, 3–5 years in P. vivax). Relapse does not occur with ..................
A

P. Falciparum.

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14
Q

In the erythrocytic cycle, with successive
broods of merozoites appearing at :
every 72hrs (3days)(quartan malaria) (P. ……..)

or 48hr(2days) intervals (tertian malaria)(P……., P……….)

or every 24hrs (P. ………)

A

P.malariae
P.ovale, P.vivax,
P.knowlesi,

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15
Q

What is Schizont in malaria?

A

a cell formed from a trophozoite during the asexual stage of the life cycle of sporozoan protozoans, such as the malaria parasite.

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16
Q

P. ………….infects RBCs of all ages and causes high levels of parasitemia;

A

P.falciparum

17
Q

what are the clinical findings for someone with malaria

A
inc respiratory rate
enlarged spleen
enlarged liver
anemia
MILD jaundice
perspiration(sweating)
fever
18
Q

what is the main symptom for malaria?

A

fever

19
Q

schizont=

A

multiple merozoites in RBC

20
Q

in which type of plasmodium do trophozoites (ring shape) appear?

A

P.falciparum

21
Q

the crescent/banana shaped gametocytes appear in which plasmodium ?

A

P.falciparum

22
Q

schuffner dots appear in which plasmodium?

A

P.vivax and P.ovale

23
Q

in malaria the form of plasmodia transmitted from mosquito to human is …..?

A

sporozoite

24
Q

Which of the following regions of the world has the highest

burden of severe P. falciparum malaria?

A

sub-saharan africa

25
Q

Maurer’s dots and trophozoite rings are observed in which type of plasmodium?

A

P.falciparum

26
Q

schuffner’s dots pigments are observed in which type of plasmodium?

A

P.vivax and P.ovale