macromolecules Flashcards

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1
Q

locations of macromolecules in the cell

A

lipids - cell membrane

nucleic acids - DNA/RNA

proteins - everywhere

carbohydrates - energy source, in the cell wall

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2
Q

Protein monomer and covalent bond

A

amino acids, peptide bonds

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3
Q

nucleic acid monomer and covalent bond

A

nucleotides linked by phosphodiester bonds

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4
Q

carbohydrate monomer and covalent bonds

A

monosaccharides linked by glycosidic bonds

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5
Q

lipds

A

fatty acids linked by ester linkages

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6
Q

what part of existing amino acid is important for forming a bond with the next one

A

the carboxyl group - N -> C directionality

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7
Q

what part of existing amino acid is important for forming a bond with the next one

A

the carboxyl group - N -> C directionality

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8
Q

directionality of nucleic acids

A

5’ - 3’, new nucleotides added to 3’ end of existing

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8
Q

directionality of nucleic acids

A

5’ - 3’, new nucleotides added to 3’ end of existing

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9
Q

carbohydrate directionality

A

4’ to 1’ (4’ end of incoming added to 1’ end of 1st monosaccharide

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10
Q

carbohydrate directionality

A

4’ to 1’ (4’ end of incoming added to 1’ end of 1st monosaccharide

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11
Q

why do macromolecules assemble in the cell?

A

non-covalent interactions

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12
Q

non covalent interactions that could occur between water and phospholipid head

A

ion-pd, pd-pd, hydrogen, ion-pd is most likely

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13
Q

what nc interactions could occur between water and phospholipid tails?

A

PD-ID

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14
Q

nc interaction lipid tails w/ each other

A

ID-ID

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15
Q

nc interactions water molecules w/ each other

A

H bonds

16
Q

lipid bilayer

A

heads and double tails

17
Q

liposome

A

mixed lipid types, artificially made

18
Q

micelle

A

like a beach ball just heads on the outside, bulky heads and single tails

19
Q

enthalpy

A

how strongly bonded a system is

20
Q

entropy

A

freedom of components of a system

21
Q

what entropy and enthalpy mean spontanaety

A

positive entropy, negative enthalpy

22
Q

what entropy and enthalpy mean spontanaety

A

positive entropy, negative enthalpy

23
Q

what is the largest contributer to system stability in bilayer formation?

A

entropy of water - wants maximum mobility/freedom

24
Q

hydrophobic effect

A

tendancy of non polar groups to cluster together away from water - increases system stability by increasing the entropy of water

25
Q

hydrophobic effect

A

tendancy of non polar groups to cluster together away from water - increases system stability by increasing the entropy of water

26
Q

three symbol things that describe system stability/spontenaety

A

gibbs free energy - negative if spont

H enthalpy - strength of bonds

S entropy - motionaly free vs motionaly restricted

27
Q

molecules that can typically pass through the membrane

A

small, non-polar molecules

28
Q

types of transport

A

active transport (req energy)
- can be primary (directly using ATP) or secondary (using electrochem gradients etc created by ATP to pump)

passive transport along concentration gradient (not req energy)
- can be simple diffusion through membrane or facilitated diffusion through channel proteins (faster)

29
Q

important things about channel proteins

A

can be open or gated

selective

molecules must interact with the protein channel

provide a hydrophilic passageway

generally faster than carrier proteins

30
Q

carrier proteins

A

gated

open and closed formations, undergoes conformational change to open and close protein