macromolecules Flashcards

1
Q

locations of macromolecules in the cell

A

lipids - cell membrane

nucleic acids - DNA/RNA

proteins - everywhere

carbohydrates - energy source, in the cell wall

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2
Q

Protein monomer and covalent bond

A

amino acids, peptide bonds

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3
Q

nucleic acid monomer and covalent bond

A

nucleotides linked by phosphodiester bonds

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4
Q

carbohydrate monomer and covalent bonds

A

monosaccharides linked by glycosidic bonds

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5
Q

lipds

A

fatty acids linked by ester linkages

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6
Q

what part of existing amino acid is important for forming a bond with the next one

A

the carboxyl group - N -> C directionality

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7
Q

what part of existing amino acid is important for forming a bond with the next one

A

the carboxyl group - N -> C directionality

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8
Q

directionality of nucleic acids

A

5’ - 3’, new nucleotides added to 3’ end of existing

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8
Q

directionality of nucleic acids

A

5’ - 3’, new nucleotides added to 3’ end of existing

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9
Q

carbohydrate directionality

A

4’ to 1’ (4’ end of incoming added to 1’ end of 1st monosaccharide

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10
Q

carbohydrate directionality

A

4’ to 1’ (4’ end of incoming added to 1’ end of 1st monosaccharide

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11
Q

why do macromolecules assemble in the cell?

A

non-covalent interactions

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12
Q

non covalent interactions that could occur between water and phospholipid head

A

ion-pd, pd-pd, hydrogen, ion-pd is most likely

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13
Q

what nc interactions could occur between water and phospholipid tails?

A

PD-ID

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14
Q

nc interaction lipid tails w/ each other

A

ID-ID

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15
Q

nc interactions water molecules w/ each other

16
Q

lipid bilayer

A

heads and double tails

17
Q

liposome

A

mixed lipid types, artificially made

18
Q

micelle

A

like a beach ball just heads on the outside, bulky heads and single tails

19
Q

enthalpy

A

how strongly bonded a system is

20
Q

entropy

A

freedom of components of a system

21
Q

what entropy and enthalpy mean spontanaety

A

positive entropy, negative enthalpy

22
Q

what entropy and enthalpy mean spontanaety

A

positive entropy, negative enthalpy

23
Q

what is the largest contributer to system stability in bilayer formation?

A

entropy of water - wants maximum mobility/freedom

24
hydrophobic effect
tendancy of non polar groups to cluster together away from water - increases system stability by increasing the entropy of water
25
hydrophobic effect
tendancy of non polar groups to cluster together away from water - increases system stability by increasing the entropy of water
26
three symbol things that describe system stability/spontenaety
gibbs free energy - negative if spont H enthalpy - strength of bonds S entropy - motionaly free vs motionaly restricted
27
molecules that can typically pass through the membrane
small, non-polar molecules
28
types of transport
active transport (req energy) - can be primary (directly using ATP) or secondary (using electrochem gradients etc created by ATP to pump) passive transport along concentration gradient (not req energy) - can be simple diffusion through membrane or facilitated diffusion through channel proteins (faster)
29
important things about channel proteins
can be open or gated selective molecules must interact with the protein channel provide a hydrophilic passageway generally faster than carrier proteins
30
carrier proteins
gated open and closed formations, undergoes conformational change to open and close protein