M7 Caries Flashcards

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1
Q

what is plaque described as?

A

a multi-species biofilm

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2
Q

what is viridans group streptococci known as?

A

oral streptococci

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3
Q

what oral streptococci is found in the tooth fissures?

A

streptococcus mutans

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4
Q

streptococcus mutans haemolytic type?

A

alpha

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5
Q

what oral streptococci is found on the tongue?

A

streptococcus salivarius

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6
Q

streptococcus salivarius haemolytic type?

A

alpha

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7
Q

what oral streptococci is found in abscesses/plaque?

A

streptococcus anginosus

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8
Q

streptococcus anginosus haemolytic type?

A

beta

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9
Q

what oral streptococci is found on the tooth/biofilm?

A

streptococcus sanguinis

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10
Q

streptococcus sanguinis haemolytic type?

A

alpha

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11
Q

what type of bacteria are oral streptococci?

A

facultative and obligate anaerobes

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12
Q

what properties of streptococcus mutans make it effective in causing caries?

A

acidogenic, acidoduric, production of extracellular polysaccharides

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13
Q

what type of respiration is happening in caries?

A

anaerobic respiration and production of lactic acid

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14
Q

define acidogenic

A

produces acid from sugar at a HIGH RATE

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15
Q

define acidoduric

A

can tolerate high concentrations of acid

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16
Q

what does s.mutans have the largest number of genes associated with?

A

sugar transport and utilisation

17
Q

what are necessary for adhesion of streptococcus strains in the plaque biofilm?

A

glucans and fructans

18
Q

what are fructans and glucans?

A

they are extracellular polymeric substances that are present on the surface of bacteria and are necessary for adhesion of streptococcus strains in the plaque biofilm

19
Q

what is GTF and what type of bacteria has GTF on its surface?

A

GTF = glucosyltransferase and S.mutans have them present of their surface

20
Q

what is FTF ?

A

FTF = fructosyltransferase

21
Q

what are the key proteins involved in the attachment of bacteria in the plaque biofilm?

A

GBP, GTF and protein anitgens

22
Q

what is GBF?

A

glucan binding proteins

23
Q

4 species of bacteria that produce lactic acid?

A

oral streptococci, actinomyces, lactobacilli, Rothia denticariosa

24
Q

What species of bacteria is associated with dentinal caries?

A

lactobacilli

25
Q

What species of bacteria is associated with root surface caries?

A

actinomyces and rothia denticariosa

26
Q

describe lactobacilli?

A

gram positive, variable rod shapes, acidoduric and acidogenic,facultative anaerobe poor adhesion

27
Q

lactobacilli fermentation groups?

A

homolactic, heterolactic, facultative heterolactic

28
Q

homolactic fermentation?

A

only lactic acid produced

29
Q

heterolactic fermentation?

A

lactic acid and others produced

30
Q

facultative heterolactic fermentation?

A

normally only lactic but can switch

31
Q

what are the 3 correlations of lactobacilli and dentinal caries?

A

no.s of lactobacilli:
increase as S.mutans fall
high when carious lesions are high
increase with carbohydrate intake

32
Q

describe actinomyces?

A

gram positive, variable rod shapes, found sub- and supra-gingivally, facultative anaerobe

33
Q

what are the 2 correlations of actinomyces and root surface caries?

A

no.s of actinomyces:
found sub and supra-gingivally
increase if gingiva is reduced

34
Q

why is the correlation between actinomyces and root surface carie now questionable?

A

because of the polymicrobial nature of root surface caries