M5 Integ Flashcards
Integumentary
表皮
Layers of epidermis (from superficial to deep)
[CLGSB: come let’s get Sun burnt]
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale
Thin (hairy) skin
Cover most area
Thick (hairless) skin
Cover other areas: palms, palmar surface of digits and soles
Sole
腳底
4 major types of cells for epidermis
Keratinocytes, melanocytes, intro epidermal macrophages (langerhan’s cell), tactile epithelial cells(Merkel cells)
Keratinocytes
The outermost layer of skin and originate from stem cells in the basal layer
The function of keratinocytes
- Protection -physical barrier against environment damage
- Keratin production: produce a kind of protein to make skin more strength and flexible
- Waterproofing 防水= produce lipids to prevent water loss
Keratinisation
The life cycle of keratinocytes角化
Keratinisation = the life cycle of keratinocytes
- Cell division in the basal layer to make keratinocytes
- Keratin cycle move up through the epidermal layers
- Produce more keratin but lose their organelles胞器and flatten as they migrate upwards
- Dead when reaching the surface and form a protective layer
Melanocytes
黑色素細胞
Melanin
黑色素
Albinism
白化症
Vitiligo
白斑
Ultraviolet light
紫外線
Mechanoreceptor
機械感受器
Light tough
Hair follicles毛囊
Indentation & slipping
壓痕&滑動:Meissner corpuscles
Vibration
振動:Pacinian corpuscles
Texture understanding
紋理理解: Merkel complexes
Stretch
伸展:Ruffini corpuscles
Tactile epithelial cells
觸覺上皮細胞
Nociceptory
Help signal pain傷害感受器
Dermis
真皮
Collagen
膠原
Dermis is connective tissue containing ___and ___
Collagen & elastic fibers
Two regions of dermis
Papillary region &reticular region
The function of papillary region
The formation of fingerprints &release growth factors for epidermal cell growth and differentiation分化
The composition of papillary region
House capillaries微血管&thermoreceptor溫度感受器& meissner’s corpuscles
The function of reticular region
Provide nutrients to skin & temperature regulation &protect skin
The composition of reticular region
Dense irregular connective tissue &pacinian corpuscles
Subcutaneous
皮下
The function of subcutaneous
Temperature regulation, protection, energy storage and administration of medication
Attaches the skin to underlying tissue and organs
The parts of a hair
Shaft軸,follicle, a root that penetrates into the dermis
The part of hair in the dermis includes 2 sheath
An epithelial root sheath & A dermal root sheath鞘
The function of hair
- Protection
- Sensory function
- Thermoregulation
- Communication
Thermoregulation
溫度調節
Aangen
生長期
Quiescence
靜止
Apoptosis
細胞凋亡
Regression
回歸
Catagen
退化
Telogen
休止
Effluvium
脫髮
Producer of nail
Keratinised epidermal cell
The structure of nail
Free edge &transparent透明nail body(plate)with a whitish lunula at its base &nail root embedded in a fold of skin
The function of nail
Protect the digits &contribute to tactile sensation促進觸覺
4 types of gland for skin
- sebaceous (oil) glands
- Eccrine sweet gland
3, apocrine sweat glands - Ceruminous glands
Sebaceous(oil) glands
皮脂腺(油)和hair follicles相連
Eccrine sweat gland
小汗腺
The function of eccrine sweat gland
Secrete sweat to regulate body temperature
Three main skin area have apocrine sweat glands
Armpits腋窩
Nipples乳頭
Genital area生殖器
The function of apocrine sweat glands
Produce a thick milky sweat containing fats & protein
Puberty
青春期
Ceruminous gland
耵聹腺:Modified apocrine glands
The function of ceruminous gland
Protect ear canal against physical damage and microbial invasion
Epidermis
表皮
Epidermal wound healing
表皮傷口癒合
Chemical mediator
化學介質
Proliferation
增生
Differentiation
分化
Deep wound
Injury extends to the dermis and subcutaneous layer
3 major stages of deep wound healing
- inflammation
- Proliferative
- Remodeling
Remodeling
改造
Homeostasis stage
止血
Cessation
停止
Vasoconstriction
血管收縮
Platelet
血小板
Fibroblasts
纖維母細胞
Endothelial cells
內皮細胞
Leukocytes
白血球
Remodelling Phase
改造階段
Metalloproteinases
金屬蛋白酶(MMP)
fibroblast
角質
Collagen
膠原蛋白
provisional
暫時
apoptosis
細胞凋亡
Thermoregulation
體溫調節
Vitamin D3 is the most effective in…
raising and maintaining the serum concentration of calcitriol
提高和維持骨化三醇的血清濃度
yolk
蛋黃
crack
開裂
Dehydration
脫水
Subcutaneous
皮下的
brittle
脆
Botox/Clostridium botulinum
肉毒桿菌
botulinum toxin
肉毒桿菌毒素
corrosive
腐蝕性