M5 Integ Flashcards
Integumentary
表皮
Layers of epidermis (from superficial to deep)
[CLGSB: come let’s get Sun burnt]
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale
Thin (hairy) skin
Cover most area
Thick (hairless) skin
Cover other areas: palms, palmar surface of digits and soles
Sole
腳底
4 major types of cells for epidermis
Keratinocytes, melanocytes, intro epidermal macrophages (langerhan’s cell), tactile epithelial cells(Merkel cells)
Keratinocytes
The outermost layer of skin and originate from stem cells in the basal layer
The function of keratinocytes
- Protection -physical barrier against environment damage
- Keratin production: produce a kind of protein to make skin more strength and flexible
- Waterproofing 防水= produce lipids to prevent water loss
Keratinisation
The life cycle of keratinocytes角化
Keratinisation = the life cycle of keratinocytes
- Cell division in the basal layer to make keratinocytes
- Keratin cycle move up through the epidermal layers
- Produce more keratin but lose their organelles胞器and flatten as they migrate upwards
- Dead when reaching the surface and form a protective layer
Melanocytes
黑色素細胞
Melanin
黑色素
Albinism
白化症
Vitiligo
白斑
Ultraviolet light
紫外線
Mechanoreceptor
機械感受器
Light tough
Hair follicles毛囊
Indentation & slipping
壓痕&滑動:Meissner corpuscles
Vibration
振動:Pacinian corpuscles
Texture understanding
紋理理解: Merkel complexes
Stretch
伸展:Ruffini corpuscles
Tactile epithelial cells
觸覺上皮細胞
Nociceptory
Help signal pain傷害感受器
Dermis
真皮
Collagen
膠原
Dermis is connective tissue containing ___and ___
Collagen & elastic fibers
Two regions of dermis
Papillary region &reticular region
The function of papillary region
The formation of fingerprints &release growth factors for epidermal cell growth and differentiation分化
The composition of papillary region
House capillaries微血管&thermoreceptor溫度感受器& meissner’s corpuscles
The function of reticular region
Provide nutrients to skin & temperature regulation &protect skin
The composition of reticular region
Dense irregular connective tissue &pacinian corpuscles
Subcutaneous
皮下
The function of subcutaneous
Temperature regulation, protection, energy storage and administration of medication
Attaches the skin to underlying tissue and organs
The parts of a hair
Shaft軸,follicle, a root that penetrates into the dermis