Lysozyme Flashcards
1
Q
What occurs in step 1?
A
- Asp52 acts a nucleophile, displacing the GlcNAc
- Glu35 protonates the GlcNAc to facilitate its departure
2
Q
What is Asp52 analogous to?
A
Ser195 of chymotrypsin
3
Q
What occurs in step 2?
A
- Glu35 acts as a general base to facilitate the attack of water
- Asp52 is displaced and product is generated
4
Q
What happens after step 1?
A
First product is released
5
Q
What happens before step 2?
A
H2O is added
