Citric Acid Cycle

Question 1

Reactant in step 1

Answer 1

Oxaloacetate

Question 2

Product in step 1

Answer 2

Citrate

Question 3

Reactant in step 2

Answer 3

Citrate

Question 4

Product in step 2

Answer 4

Isocitrate

Question 5

Reactant in step 3

Answer 5

Isocitrate

Question 6

Product in step 3

Answer 6

alpha-ketoglutarate

Question 7

Reactant in step 4

Answer 7

alpha-ketoglutarate

Question 8

Product in step 4

Answer 8

Succinyl-CoA

Question 9

Reactant in step 5

Answer 9

Succiny-CoA

Question 10

Product in step 5

Answer 10

Succinate

Question 11

Reactant in step 6

Answer 11

Succinate

Question 12

Product in step 6

Answer 12

Fumarate

Question 13

Reactant in step 7

Answer 13

Fumarate

Question 14

Product in step 7

Answer 14

L-malate

Question 15

Reactant in step 8

Answer 15

L-malate

Question 16

Product in step 8

Answer 16

Oxaloacetate

Question 17

Enzyme in step 1

Answer 17

Citrate synthase

Question 18

Enzyme in step 2

Answer 18

Aconitase

Question 19

Enzyme in step 3

Answer 19

Isocitrate dehydrogenase

Question 20

Enzyme in step 4

Answer 20

alpha-ketoglutarate dehydrogenase complex and TPP, lipoate, FAD

Question 21

Enzyme in step 5

Answer 21

Succinyl-CoA synthetase

Question 22

Enzyme in step 6

Answer 22

Succinate dehydrogenase

Question 23

Enzyme in step 7

Answer 23

Fumarase

Question 24

Enzyme in step 8

Answer 24

Malate dehydrogenase

Question 25

Coenzyme in step 4

Answer 25

- CoA-SH in, CO2 out | - NAD+ -> NADH

Question 26

Coenzyme in step 5

Answer 26

- GDP + P -> GTP | - CoA-SH released

Question 27

Coenzyme in step 6

Answer 27

FAD -> FADH2

Question 28

Coenzyme in step 7

Answer 28

H2O in

Question 29

Coenzyme in step 8

Answer 29

NAD+ -> NADH and H+

Question 30

Is step 1 exergonic or endergonic?

Answer 30

Exergonic

Question 31

What type of reaction is step 2?

Answer 31

Isomerization

Question 32

What type of reaction is step 3?

Answer 32

Oxidative decarboxylation

Question 33

What type of reaction is step 4?

Answer 33

Oxidative decarboxylation

Question 34

What inhibits the alpha-ketoglutarate dehydrogenase complex?

Answer 34

NADH and succinyl-CoA

Question 35

What type of reaction is step 5?

Answer 35

Substrate level phosphorylation

Question 36

Are GTP and ATP energetically different or equivalent?

Answer 36

Equivalent

Question 37

Which enzyme in the CAC is membrane bound in the mitochondria?

Answer 37

Succinate dehydrogenase (enzyme of step 6)

Question 38

Is step 8 exergonic or endergonic?

Answer 38

Endergonic

Question 39

Coenzyme in step 1

Answer 39

CH3-C=O-SCoA + H2O -> HSCoA + H+

Question 39

Coenzyme in step 2

Answer 39

H2O released and H2O in

Question 39

Coenzyme in step 3

Answer 39

- H+ and NAD+ -> NADH and H+ | - CO2 released