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HDM Midterm - Brett > Lymphoid Tissue > Flashcards

Lymphoid Tissue Flashcards

1
Q

What makes a lymphoid organ primary ?

A

When it produces lymphocytes

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2
Q

What are the two primary lymphoid organs

A

Thymus and red bone marrow

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3
Q

What are secondary lymphocytes?

A

Diffuse lymphoid tissue where lymphocytes are activated in response to antigens

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4
Q

__________________ cells are most common where the body meets the outside world

A

Non-encapuslated

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5
Q

Non-encapsulated diffuse tissue is found where?

A

GI tract, genitourinary tract, respiratory passages

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6
Q

What is the difference between primary and secondary nodules

A

Primary nodules are dark in the middle and have a high concentration of naive cells; secondary nodules have a germinal center which is a much paler color and forms a corona

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7
Q

What area are non-stratified squamous cells found in?

A

Mouth, anus, vagina, respiratory tract

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8
Q

How are germinal centers different than mantles?

A

Germinal center is pale while the mantle is more dense

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9
Q

Where do memory cells collect in secondary nodules?

A

Mantle

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10
Q

What cell type is not found in the germinal center?

A

T cells

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11
Q

What is one example of non-encapsulated lymphoid tissue aggregates?

A

The tonsils

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12
Q

From most distal to most proximal what are the order of the tonsils?

A

Pharyngeal, palatine, lingual

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13
Q

What do the tonsils do?

A

They protected against inhaled or ingested substances

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14
Q

What tonsil section is characterized by large number of stratified squamous cells and 10-20 deep tonsillar crypts?

A

Palatine

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15
Q

Which two sections of tonsils are most similar?

A

Lingual and palatine. They both have crypts, stratified squamous epithelium

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16
Q

What tonsils have pseudostratified columnar ciliated epithelium?

A

Phayngeal

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17
Q

What does MALT stand for? Where is it found?

A

Mucosa-associated lymphoid tissue

It is in the GI, respiratory airways, and urinary tract

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18
Q

Where is GALT found? What does it stand for?

A

Gut-associated lymphoid tissue

It is found in the SI particularly the ileum, and it is characterized bu abundance of villi

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19
Q

What are peyers patches associated with?

A

GALT

20
Q

The appendix is similar to what?

A

The peyer’s patches

21
Q

What are the primary lymph organs?

A

Thymus and red bone marrow

22
Q

The thymus is a bilobed structure in the

A

Mediastinum

23
Q

When does involution occur and what is it

A

The process of decreased thymus activity as it becomes filled with adipose tissue

Until puberty

24
Q

The thymus is made of lobes called ________

A

Septa

25
Q

The darker staining region in the thymus is the ______ __________ while the lighter staining area is the the _____ _______

A

Outer cortex, inner medulla

26
Q

The ___________________ is the site of t-lymphocyte maturation

A

Thymic

27
Q

What cells produce the cytoreticulum?

A

Cortical (stellate) cells

28
Q

What cells form the cortical compartment of the thymus

A

Subcapsular (squamous)

29
Q

What is tightly packed with whorls of TECs?

A

Hassall’s copuscles

30
Q

Where do cytokines that finalize maturation of T cells come from?

A

Hassal’s copuscles

31
Q

Where are mature T cells found right before they enter circulation?

A

Medulla

32
Q

What are 2 major functions of the spleen?

A

Reservoir for platelets, recycling center for erythrocytes

33
Q

Periarteriolar lymphoid sheaths are made of what?

A

T cells

34
Q

The most dense zone outside of the GC is the __________

A

Corona/mantle zone

35
Q

The transition from white to red pulp is called _______________

A

Marginal zone

36
Q

The red pulp is perfused and is in charge of what function?

A

Blood filtration and erythrocyte turn over

37
Q

What are splenic cords? What are sinusiods?

A

Splenic cords are branches of the splenic artery that just dead end.

Sinusiods are barrel like structures made of stave cells that allow blood to flow through

38
Q

What cleans up the recycled cells that are left in the spleen?

A

Macrophages

39
Q

What is swelling made of?

A

Lymph

40
Q

What is the function of the hilum in lymph nodes?

A

The exit for lymph

41
Q

The outer cortex does what?

A

Receives lymph from surrounding area

42
Q

The central medulla is responsible for what?

A

Collecting lymph on its way to the hilum

43
Q

Where does blood and lymph meet in the nodes?

A

Cortex

44
Q

What are the canals that allow lymph to get deeper into the lymph nodes

A

Tabeculae

45
Q

The ____________ ________ is in the lymph node cortex and allows space for lymph to flow

A

Subcapsular sinus

46
Q

Where are high endothelial venules found? What cell type are they?

A

Paracortex, simple cuboidal (allow movement of lymphocytes)

HDM Midterm - Brett (10 decks)

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