Intro to Immunology Flashcards
(33 cards)
Atopic diseases are more commonly known as what?
Allergies
What are the 4 main roles of the immune system?
- Defense against infections
- Defense against tumors
- Inflammatory responses
- Host v. non-host
What does CD stand for?
Cluster of differentiation
The messengers of the immune system are commonly known as _____________
Cytokines
The two main types of immunity?
Innate and adaptive
What are the subcategories of adaptive immunity?
Passive (artificial and natural)
Active (artificial and natural)
What is the fast immune response? Slow?
Innate immune system responds on the hours timeline while adaptive responds on the day timeline
Is adaptive immunity specific or non-specific?
Specific, it is the learning immunity
What is the default state of innate immunity?
It is turned off unless needed
Innate immune cells generally follow what lineage?
Myeloid stem cells
Eosinophils differentiate in response to ___________
IL5
Eosinophils make up ________ % of white blood cells
1-6
Eosinophils are short-lived, they usual live in circulation for ______________
8-12 hours
What was the primary responsibility of eosinophils? What do they do now?
Multicellular parasites, atopic diseases
Basophils are non-_____________ and generally have ____________ nucleus
Phagocytic, bi-lobed
(T/F) basophils are granulated
T
What are basophils stained with?
Methylene blue
What is one of the major compounds released by basophils?
Histamine
Mast cells often live in ______________
Tissues
What are the two types of mast cells?
Tissue and mucosal
Mast cells play a role in what 2 responses?
Inflammatory and atopic
Mast cells granules are made of:
Histamine, proteases, heparin, TNF
Mast cells serve to active more
WBCs
What lineage do NK cells come from?
Lymphoid
