Lymphoid Structures I

Question 1

lymph node

Answer 1

encapsulated

filtration macros
store B and T cell
immune activation

Question 2

follicle of lymph node

Answer 2

site of B cells

Question 3

primary follicle

Answer 3

dense and dorminant

B cells

Question 4

secondary follicle

Answer 4

pale germinal center

active B cell proliferation

Question 5

medulla of lymph node

Answer 5

cords - packed lymphos and plasma cells

sinuses - communicate with efferent lymphatics
-contain reticular cells and macros

Question 6

paracortex

Answer 6

holds T cells

has high endothelial venules - B and T cell enter from blood

Question 7

not well developed in digeorge

Answer 7

high endothelial venules

Question 8

cervical lymph nodes

Answer 8

head and neck

Question 9

hilar lymph nodes

Answer 9

drain lungs

Question 10

mediastinal lymph nodes

Answer 10

drain trachea and bronchi

Question 11

axillary lymph nodes

Answer 11

drain upper limb, breast, skin above umbilicus

Question 12

celiac lymph nodes

Answer 12

liver, stomach, spleen, pancreas, upper duodenum

Question 13

superior mesenteric nodes

Answer 13

drain lower duodenum, jejunum, ileum, colon to splenic flexure

Question 14

inferior mesenteric nodes

Answer 14

drain colon from splenic flexure to upper rectum

Question 15

internal iliac nodes

Answer 15

drain lower rectum to anal canal - above pectinate line

bladder, vagina (middle third), and prostate

Question 16

para-aortic nodes

Answer 16

drain testes, ovaries, kidneys, uterus

Question 17

superficial inguinal nodes

Answer 17

drain anal canal - below pectinate line

skin below umbilicus, scrotum

Question 18

popliteal nodes

Answer 18

drain dorsolateral foot and posterior calf

Question 19

thoracic duct

Answer 19

drain 3/4 body

-to junction left subclavian and internal jugular vein

Question 20

sinusoid of spleen

Answer 20

vascular channel in red pulp with fenestrated basement membrane

Question 21

T cells in spleen

Answer 21

in periarteriolar lymphatic sheath - white pulp

Question 22

B cells in spleen

Answer 22

in follicles of white pulp

Question 23

marginal zone

Answer 23

of spleen
-between red and white pulp

APC and specialized B cells

APC capture blood-borne Ags for recognition

Question 24

red pulp of spleen

Answer 24

location of RBCs

Question 25

splenic dysfunction

Answer 25

low IgM
low complement activation
low C3b
susceptible to encapsulated organism

Question 26

encapsulated organisms

Answer 26

strep pneumo
h. flu type b
n. meningitidis
e. coli
salmonella
klebsiella
group B strep

Question 27

changes postsplenectomy

Answer 27

howel jolly bodies - nuclear remnants

thrombocytosis

lymphocytosis

Question 28

thymus

Answer 28

site T cell differentiation and maturation

from 3rd pharyngeal pouch

Question 29

thymus cortex

Answer 29

dense - immature T cells

Question 30

thymus medulla

Answer 30

pale - mature T cells

Question 31

hassal corpuscle

Answer 31

in thymus

epithelial reticular cells

Question 32

T cell

Answer 32

thymus

Question 33

B cells

Answer 33

bone marrow