Lymphoid Structures I Flashcards

1
Q

lymph node

A

encapsulated

filtration macros
store B and T cell
immune activation

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2
Q

follicle of lymph node

A

site of B cells

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3
Q

primary follicle

A

dense and dorminant

B cells

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4
Q

secondary follicle

A

pale germinal center

active B cell proliferation

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5
Q

medulla of lymph node

A

cords - packed lymphos and plasma cells

sinuses - communicate with efferent lymphatics
-contain reticular cells and macros

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6
Q

paracortex

A

holds T cells

has high endothelial venules - B and T cell enter from blood

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7
Q

not well developed in digeorge

A

high endothelial venules

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8
Q

cervical lymph nodes

A

head and neck

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9
Q

hilar lymph nodes

A

drain lungs

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10
Q

mediastinal lymph nodes

A

drain trachea and bronchi

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11
Q

axillary lymph nodes

A

drain upper limb, breast, skin above umbilicus

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12
Q

celiac lymph nodes

A

liver, stomach, spleen, pancreas, upper duodenum

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13
Q

superior mesenteric nodes

A

drain lower duodenum, jejunum, ileum, colon to splenic flexure

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14
Q

inferior mesenteric nodes

A

drain colon from splenic flexure to upper rectum

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15
Q

internal iliac nodes

A

drain lower rectum to anal canal - above pectinate line

bladder, vagina (middle third), and prostate

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16
Q

para-aortic nodes

A

drain testes, ovaries, kidneys, uterus

17
Q

superficial inguinal nodes

A

drain anal canal - below pectinate line

skin below umbilicus, scrotum

18
Q

popliteal nodes

A

drain dorsolateral foot and posterior calf

19
Q

thoracic duct

A

drain 3/4 body

-to junction left subclavian and internal jugular vein

20
Q

sinusoid of spleen

A

vascular channel in red pulp with fenestrated basement membrane

21
Q

T cells in spleen

A

in periarteriolar lymphatic sheath - white pulp

22
Q

B cells in spleen

A

in follicles of white pulp

23
Q

marginal zone

A

of spleen
-between red and white pulp

APC and specialized B cells

APC capture blood-borne Ags for recognition

24
Q

red pulp of spleen

A

location of RBCs

25
splenic dysfunction
low IgM low complement activation low C3b susceptible to encapsulated organism
26
encapsulated organisms
``` strep pneumo h. flu type b n. meningitidis e. coli salmonella klebsiella group B strep ```
27
changes postsplenectomy
howel jolly bodies - nuclear remnants thrombocytosis lymphocytosis
28
thymus
site T cell differentiation and maturation from 3rd pharyngeal pouch
29
thymus cortex
dense - immature T cells
30
thymus medulla
pale - mature T cells
31
hassal corpuscle
in thymus epithelial reticular cells
32
T cell
thymus
33
B cells
bone marrow