Lymphoid Structure Flashcards
Primary lymphoid organs are (2)
Bone Marrow
Thymus
Main source of Hematopoetic Stem Cells
Bone Marrow
Site of Maturation of B lymphocytes
Bone Marrow
Site of differentiation and Maturation of T cells
Thymus
Immature T cells are dense with
Cortex
Mature T cells and Hassall corpuscles are dense with
Medulla
Largest Secondary Lymphoid Organ
Spleen
*12 cm
*150 g
*Upper Left Quadrant
It is Responsible of removing OLD RBC and DAMAGED cells, foreign antigens from the Blood
Spleen
2 type of Splenic tissue:
Red pulp
White pulp
Splenic tissue responsible of removing OLD RBC
Red Pulp
Splenic Tissue that contains lymphoid tissue
White pulp (20%)
In Spleen’s White Pulp:
It is found in the PERIARTEIOLAR LYMPHATIC SHEATH
T cells
In Spleen’s White Pulp:
It is found in the Follicles of white pulp
B cells
B cells found in the follicles of the white pulp are STIMULATED/UNSTIMULATED BBY ANTIGENS?
UNSTIMULATED
Region between Red pulp and White Pulp by which APC awaits for capturing blood-borne pathogens.
Marginal zone
Spleen receives ___ amount of blood
350 mL/min
Central Collecting Point of Lymph fluids
Lymph nodes
Encapsulated and with Trabeculae
Lymph nodes
In Lymph nodes, it is the site of B cell localization and proliferation
Cortex
In Primary Cortex, B cell are
Mature
Unstimulated with Antigens
In Secondary Cortex, B cell are
Antigen Stimulated
With GERMINAL CENTER
In Lymph nodes, it is localized between the Paracortex (between follicles and medulla)
T cells
In lymph nodes, it contains the medullary cords and sinuses
Medulla
Multiplication of Lymphocytes
Lymphopoiesis
Lymphoiesis occurs in
Secondary Lymphoid Organ
If the lymphocytes are produced by BM it is
Antigen dependent / Antigen Independent
Antigen Independent
What cells are found after Postsplenectomy
Howell-Jowell bodies
In Postsplenectomy, Plateletes are ______
Increased (released into the blood)
1/3 of Platelets are stored in Spleen
2/3 of Platelets are in blood
Patient is known remove certain part of his organ; presence of Howell Jolly bodies are seen, Thrombocytosis and Lymphocytosis
Postsplenectomy
