Hypersentivity

Question 1

Mediators: IgE
Effector Cell: Mast Cell & Basophils
Antigen Involved: Allergen
Complement Involvement: No
Mechanism: Inflammatory Mediators

Answer 1

Anaphylactic/Atopic

Question 2

Mediators: IgM and IgG
Effector Cell: WBC, RBC, Platelets
Antigen Involved: Cell Bound Antigen
Complement Involvement: Yes
Mechanism: Cell Lysis

Answer 2

Cellbound Cytotoxic (Type II)

Question 3

AIHA
HTR
HDN
ITP
Goodpasture syndrome
Rheumatic Fever

Answer 3

Type II (Cellbound cytotoxic)

Question 4

Mediators: IgM and IgG
Effector Cell: Host Tissue Cells
Antigen Involved: Soluble Antigen
Complement Involvement: Yes
Mechanism: Deposition of Ag-Ab Complex

Answer 4

Immune Complex (Type III)

Question 5

Serum Sickness
Arthus Reaction
SLE
Poststreptococcal glomerulonephritis
Polyarteritis nodosa

Answer 5

Type III (Immune Complex)

Question 6

Mediators: T cells
Effector Cell: Macrophage, APC, T cells
Antigen Involved: Sensitized Antigen
Complement Involvement: No
Mechanism: Release of Cytokines

Answer 6

Delayed Hypersentivity (Type IV)

Question 7

Contact Dermatitis
Poison Ivy
GVHD
Tuberculin Test

Answer 7

Delayed Hypersensitivity Test (Type IIV)

Question 8

4T in Delayed Hypersensitivity

Answer 8

T Cells
Transplant Rejection
TB Skin test
Touching (dermatitis)

Question 9

Bacteria Implicated in Producing Autoimmune Disease:

Rheumatic Fever

Answer 9

S. pyogenes

Question 10

Bacteria Implicated in Producing Autoimmune Disease:

Reiter Syndrome

Answer 10

C. trachomatis

Question 11

Bacteria Implicated in Producing Autoimmune Disease:

Ankylosing spondylitis

Answer 11

Enteric K. pneumoniae, Shigella

Question 12

Bacteria Implicated in Producing Autoimmune Disease:

M. pneumoniae
C. jejuni

Answer 12

Guillain Barre Syndrome