Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Histology > Lymphatics Test Three > Flashcards

Lymphatics Test Three Flashcards

1
Q

Innate Immunity?

A

Lack immune specificity and memory Response is inflammation from neutrophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Acquired Immunity?

A

Develops in response to antigens More powerful than innate Displays specificity and memory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Passive Immunity?

A

Temporary immunity due to donated antibodies-placental antibodies to fetus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Active Immunity?

A

Long lasting permanent immunity to self exposure to antigen resulting in T cells and B cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Primary lymphoid organs?

A

Thymus and bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Secondary lymphoid organs?

A

Spleen lymph nodes tonsils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the difference between a primary and secondary lymphoid follicle(nodule)?

A

Primary are spherical and tightly packed virgin B cells and dentridritic reticular cells that have no antigen exposure.

Secondary are derived from primary follicles that have been exposed to antigetns and are not present at birth.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are lymphoid follicles?

A

Not enclosed in capsule and can occur singly or in groups, site of B cell localization and proliferation, transient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is a primary follicle (nodule)?

A

Spherical tightly packed virgin B cells and dendritic reticular cells not exposed to antigens.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are secondary follicles (nodules)?

A

Nodules derived from primary follicles that have been exposed to nonself antigens-NOT present at birth.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Structure of a secondary lymph follicle?

A

Corona (cortex) composed of dense packed B lymphocytes and looks darker around the edges. Germinal center a central lighter stained region made of B lymphocytes memory B cells plasma cells dendritic reticular cells functioning as APC’s.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Vascular supply to a secondary lymph follicle?

A

Arteriole and venule supply the cortex a different arteriole and venule supply the center and lymph capillaries are NOT present.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is diffuse lymphatic tissue?

A

Made of clusters of plasma cells, macrophages, and lymphocytes in the CT stroma. Lamina propria associated lymph tissues: MALT, BALT,GALT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is aggregated lymphoid tissue?

A

Beneath and in contact with the epithelium including tonsils and peyers patches in the ileum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where do all immune cells originate?

A

Bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where do Immune cells go?

A

Immature T cells go to thymus and B cells go to specific regions in lymphoid tissues

17
Q

What are the five classes of Antibodies?

A

IgA IgD IgG IgM IgE

18
Q

Structure of an antibody?

A

Light and heavy chains, highly variable regions with a Fab fragment that recognizes the antigen, less variable region Fc fragment that binds antibody to cells

19
Q

What is the function of MHC?

A

Presentation of antigenic peptides to T cells

20
Q

MHC I?

A

Presented on surface of all cells except trophoblasts and RBC’s Requires CD8 and T cell antigen for binding

21
Q

What is MHC II?

A

Expressed on surface of B cells and APC’s. CD4+ and T cells recognize peptide gragments of foreign proteins bound to MHC II on surface of APC’s

22
Q

What are CD4+ T cells?

A

Recognize antigens bound to MHC class II molecules

23
Q

What are Helper T cells?

A

Assist CD8+ cells differentiation and assist B cell differentiation.

24
Q

What are CD8+ cells?

A

Cytolytic T cells bind to an APC releasing perforins and Fas ligand , recognize antigens bound to MHC I molecules, Undergo mitosis, Mediators of cellular immunity

25
Q

CD16+ T cells?

A

Natural Killer Cells activated T cells by tumor cell antigens they release cytokines

26
Q

What is T cell mediated immunity?

A

After the macrophage phagocytizes foreign material and presents antigens bound to MHC II complex to the helper T cell the T cell undergoes mitosis. Then the T cell attracts B cells and B cellls have access to free antigens and can undergo mitosis becoming memory B cells or plasma cells with the antibodies

27
Q

What is the difference in parenchyma and stroma?

A

Parenchyma is cells that pack areas of lymphoid organ mostly lymphocytes. Stroma is reticular fibers and cells and undiffferentiated cells and fixed/free macrophages.

28
Q

Identify

A

Trabecula of Lymph node

29
Q

Identify

A
  1. Trabecula
  2. Sub-capsular sinus
  3. Germinal center of follicle
  4. Lymph follicle in cortex
30
Q

Describe the medulla of a lymph node.

A

Irregular arrangement of loose medullary sinuses and dense medullary cords

  • Sinuses lined with macrophages
  • Cords with blood vessels lymphoblasts and plasma cells

Site of lymphocyte reentry to lymph stream

31
Q

Identify

A
  1. Trabecula
  2. Germinal Center
  3. Lymph follicle in cortex

Secondary Node

32
Q

Identify

A

Primary follicle

33
Q

What is this?

A

Medulla of a lymph node

34
Q

What is this?

A

Medulla of a lymph node

Histology (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions