Epithelium Flashcards
List general characteristics of epi tissues
Simple or stratified, classified by uniform shape of the superficial most layer. Tightly bound together, free surfaces,line body cavities, innervated tissues. Basement membrane1
Major criteria used to classify epi tissues.
Simple or stratified
Squamous, cuboidal or columnar
Could have cilia, stereocilia, or microvill
Could be keratinized or not
Characterize and compare the apical and basolateral domains of epithelium.
Apical Domains: could have cilia or microvilli apical domains face a lumen or external environment
Basolateral Domains: sides and bases have intracellular junctions and they are in contact with the BM
Describe types of specialization on apical surfaces
Microvilli:
Cilia:
Sterocilia:
Locations of Simple Squamous.
Lumina of ducts vessels and other tubular structures, makes walls of alveoli and Bowman’s capsules and inner membranes in ear.
Describe structure of microvillus.
A
Describe function of brush border.
Increase surface area to increase absorption
Describe structure of a cilia.
9 microtubule doublets surrounding a central microtubule, each doublet consists of an alpha and beta tubule alpha tubule made of 13 protofilaments, and beta made of 10-11 protofilaments, each doublet is connected by dynenin arms for movement
Describe structure of microvillus.
(Check) cross linked actin fibers, non motile
Describe function of brush border.
Move particles along in places such as respiratory system or Fallopian tubes.
Describe the basic structure for the generalized plasma membrane from Singer and Nicholson, with the arrangement of phospholipids and proteins.
Phospholipid bilayer
Recognize which phospholipid classes are found in the outer leaflet and inner leaflet of men.
Cholesterol is found in both
Describe he location and function of glycolipids in plasma membrane.
A
Describe lipid rafts.
Af
Describe glycocalyx, it location and functions.
A
Differentiate peripheral and integral proteins including transmembrane an major characteristics
Peripheral proteins are found on the surface of the membrane
Integral proteins are embedded within but do not go all the way through
Transmembrane proteins go through the membrane
Differentiate categories of transport proteins
A
List major mechanisms for moving materials across meme and indicate if they are energy dependent and if they need transporters.
Active Transport: needs carrier requires energy
Facilitated Transport: no energy, but needs carrier
Simple Diffusion: no energy no carrier
Osmosis: no energy uses aquaporins move water across a membrane
Describe basolateral modifications:
Basolateral modifications are hemidesmosomes linking the basal surface to the Basement membrane and desmosomes linking the lateral surfaces of cells together
Simple Cuboidal location.
May have brush border such as kidney tubules, found on ovary, epithelium of retina, choroid plexus, anterior capsule of lens
Location of Simple Columnar.
Could have microvilli, ciliated columnar is found in upper respiratory tract Fallopian tubes, sinuses and central canal of spinal cord. Non ciliated is in digeeestive tract, gall bladder and excretory ducts.
Location of Stratified Squamous.
Keratinized: epidermis and in cornia,
Non-Keratinized: esophagus vagina mouth tongue and epiglottis
Stratified Cuboidal Location.
Rarely found, but found in male urethra
Location of Stratified Columnar.
Rarely found- but found in adult sweat glands, fornix of eye, male reproductive/urinary tracts, pharynx and epiglottis
Location of Psuedostratified Epi.
Ciliated found in trachea
Pseudostratified with. Stereocilia found in epididymis
Transisitional epi location.
Urinary system.
Junctional complexes are associated with which cellular domains? A.Apical B. Basolateral C.Basal only D.Lateral only
Basolateral
Transitional epi is associate with which f the following? A.respiratory B. Lymphatic C.Cardio D. Uriary
Urinary
Not commonstratified cuboidal may e found in which area? A.Vaginal Epithelium B. Male urethra C. Urinary bladder D. Kidney tubules
A. Part of male urethra
Lightly keratinized stratified squamous epi is in which location?
A. Vaginal epithelium
B. Skim
C.larynx
Vaginal Epithelium
Basal Latina is associated with which collagen?
Type 4
Which cell adhesion molecules is associated with zonal occludens and desmosomes? A. Cadherins B itegrins C. Selections D. Immunoglobulin
Cadherins
