Lymphatics Flashcards

1
Q

Describe the structure of capillaries:

A
Thinner walls
Numerous and highly branched
Narrow diameters
Narrow lumen
Spaces between endothelium
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2
Q

What is the reason for capillaries having thin walls?

A

Decreases diffusion distance for gases

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3
Q

What is the reason for capillaries being numerous and highly branched?

A

Large surface area for exchange of gases

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4
Q

What is the reason for capillaries having spaces between endothelium?

A

So white blood cells can pass through

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5
Q

What is the reason for capillaries having a narrow lumen?

A

So red blood cells are squashed against the side of the capillary, decreasing the diffusion distance for gases

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6
Q

How much interstitial fluid is generated daily from capillary filtration?

A

3 litres

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7
Q

What are the constituent parts of the lymphatic system?

A

Conducting system

Lymphoid tissue

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8
Q

What is the role of lymphatic capillaries?

A

To collect interstitial fluid created from capillary flitration

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9
Q

What is the structure of a lymphatic capillary?

A

Blind-ended, bulbous tubes lined with endothelial cells

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10
Q

What is the function of uni-directional valves in the lymph conducting systems?

A

They prevent the backflow of lymph

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11
Q

What causes lymph to move through the conducting system?

A

Contraction of smooth muscle

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12
Q

What happens to lymph at the lymph nodes?

A

Bacteria and foreign material is removed by phagocytosis

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13
Q

What do lymph capillaries merge into?

A

Collecting lymph tubes

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14
Q

Describe the structure of lymph collecting tubes:

A

Smooth muscle and Uni-directional valves

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15
Q

Where is lymph collected from and by what is it collected?

A

Collected by lymph capillaries from the interstitial space

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16
Q

Describe the passage of lymph through the lymphatic system:

A
Collected in lymphatic capillary
Merge into collecting vessel
Afferent lymphatics take to lymph node
Through thoracic duct
Into subclavian vein
17
Q

What is meant by the term afferent lymphatic?

A

Uni-directional

18
Q

Where does lymph re-enter the circulatory system?

A

Subclavian vein

19
Q

What is the role of the lymphatic conducting system?

A

Carries lymph to the nodes and back into the bloodstream

20
Q

Lymph nodes are considered as what type of lymphoid tissue?

A

Secondary

21
Q

The thymus and bone marrow are considered as what type of lymphoid tissue?

A

Primary

22
Q

What is oedema?

A

Swelling in the tissues due to excess fluid in the interstitial space

23
Q

What is kwashiorkor?

A

A malnourished person does not receive enough protein, therefore, osmotic potential is decreased and less water is pulled into blood capillary. This excess tissue fluid causes a ‘puffed’ belly effect

24
Q

What can cause oedema?

A

When the rate of capillary filtration is greater than the rate of lymphatic drainage

(Therefore, very fast filtration or dysfunctional drainage)

25
Q

What are secondary lymphoid organs of the body?

A

Lymph nodes, Payers patches, Tonsils and Adenoids, maintain mature naïve lymphocytes and initiate acquired immune response, sites of lymphatic activation

26
Q

Why might capillary filtration be increased?

A

An osmotic pressure difference and the capillary hydrostatic pressure

27
Q

What is elephantiasis?

A

Where nematode worms are present in the lymphatic vessels causing lymph to build up

28
Q

What are primary lymphoid organs of the body?

A

Thymus and Bone marrow, involved in production and early selection of lymphocytes, generate lymphocytes from immature cells