lymphatic system pt 2 - unit 3 Flashcards
3 lymphocyte cells
b, Tc, and Th
mature lymphocyte cells. undergo selection in bone marrow. involved in antibody and medicated immunity.
B cells
mature lymphocyte cells. undergo selection in thymus. “CD8+ cells.” give rise to cell medicated immunity
cytotoxic t cells
mature lymphocyte cells. undergo selection in thymus. “CD4+ cells.” help activate B and Tc. involved in antibody and cell medicated immunity.
Helper T cells
lymphocyte selection
occurs in bone marrow and thymus when a fetus/baby. we have trillions as a baby but several are killed off as antigen receptor binds to body’s natural molecules. those that don’t stay as antigens.
major histocomatability complex.
how molecules are displayed to lymphocytes.
MHC type. made by B cells and macrophages. link engulfed molecules onto MHC2 proteins and display them on cell surface as MHC2 Completes.
Type 2
T_ can bind to MHC2 via antigen receptors
Helper
MHC type. Made by all other body cells. they constantly link MHC1 proteins with molecules within themselves then placed on cell surface as MHC1 Completes.
Type 1
T_ bind to MHC1 via antigen receptor
Cytotoxic
Two types of acquired immunity
cell-medicated and antibody medicated.
immunity activated by naive T cells and carried out by Tc cells. carried against infected cells
Cell-medicated immunity
immunity activated by Th and carried out by B cells. carried against extracellular antigens.
antibody-medicated immunity
antibodies are
4 shaped proteins released by activated B cells that bind to a specific antigen that initially activated the B cell and travel through extracellular fluid.
memory cells
Th, Tc, and B cell clones that remain in body after an infection clears