Lymphatic System Flashcards
State the primary function of the lymphatic system.
- Production, maintenance, and distribution of lymphocytes
- Return of fluid and solutes from peripheral tissue to the blood
- Distribute hormones, nutrients, and waste products from their tissue of origin to the general circulation
List the components of the lymphatic system.
- Lymphatic vessels
- Lymph fluid
- Lymphoid organs
State how lymph is formed.
Fluid from all parts of the body (except CNS) is collected by the lymphatic vessels and returned to the blood. Lymph is primarily made of lymphocytes.
Describe how lymph is returned to the blood.
The liquid from peripheral tissue is captured by the lymphatic capillaries then carried by the larger lymphatic vessels from to the thoracic duct or the right lymphatic duct to be returned to the blood. The vessels allow one direction flow because of valves located in the vessels.
State the location of lymph nodules.
they are found beneath the epithelia lining of various organs that are open to the outside envioronment (repiratory, digestive, and urinary systems)
Describe lymph nodules and their function.
Masses of lymphoid tissue not surrounded by a fibrous capsule. They attempt to destroy bacterial and viral invaders from the outside environment.
Give an exaple of a lymph nodule.
Appendix and tonsils.
State the location of lymph nodes.
Located in regions near vital organs to detect and eliminate antigens.
Describe the function of lymph nodes.
Fibrous capsules that filter and purify lymph before it returns to the venous system.
Describe the function of the spleen.
Filters blood by removing abnormal blood cells and components, inititates an immune reponse, and stores iron from the recycled blood cells.
State the location of the spleen.
between the stomach, left kidney, and diaphragm
Define immunity.
security against a particular disease; non-suscptibility to the invasisve or pathogenic effects of foreign microorganisms or to the toxic effects of an antigenic substance.
Describe the function of the thymus.
The location of T cell maturation.
Define lymphocytes.
Leukocytes that are the primary cells of the lymphatic system comprised of T cells, B cells, and NK cells.
List the various types of T cells and state their function.
- Cytotoxic T cells - Called killer T cells, track down and attack antigens
- Memory T cells - lie dormant until a previously encountered antigen is recognized, once the antigen is recognized they immediately differentiate into cytotoxic T cells
- Suppressor T cells - Suppress the responses of other T cells and B cells
- Helper T cells - Coordinate specific and non specific defenses and stimulate cell-mediated and antibody mediated immunity
Describe the function of B cells and Memory B cells.
B cells are bone marrow derived and are activated by helper T cells through antibody mediated immunity. They are responsible for the production of and secretion antibodies. Memory B cells are formed during an initial exposure to an antigen. They lie dormant and await another exposure by the same antigen for a quicker response.
Describe the development of T cells.
- created in red bone marrow
- travel to thymus
- mature in thymus
- primary lymphocyte (80% of lymphocytes)
- represent cell-mediated immunity
Describe antibody mediated immunity.
Comprised fo B cells. Can differentiate into plasma cells that are responsible for the production and secretion of antibodies in the blood.