Lymphatic System Flashcards
What are the primary organs of the lymphatic system?
generate lymphocytes from progenitor cells
bone marrow
thymus
cloacal bursa
What are the secondary organs of the lymphatic system?
site of lymphocyte activation
lymph nodes
spleen
mucosal associated lymphoid tissue
What is the function of the lymphatic system?
to protect the body against pathogenic organisms
removal and disposal of cells
What are the actions the lympathic system is involved in?
- phagocytosis via macrophages
- production of immunologically competent cells such as antigen presenting cells and T and B cells
What is the mononuclear phagocytic system?
fixed macrophages and free macrophages
What are fixed macrophages?
sinusoids of liver, spleen and lymph nodes
reticulum of bone marrow
What are free macrophages?
blood, lung and serous cavities
How does T cell differentiation come about?
bone marrow, lymphoid stem cell
Thymus
How does B cell differentiation come about?
bone marrow, lymphoid stem cell
bursa or bone marrow
What are the cells of the lymphatic system?
lymphocytes
antigen presenting cells
stromal cells
T or F: T and B cells originate from secondary lymphatic organs?
False, PRIMARY
Where do T cells migrate to from bone marrow?
thymus
T or F: B cells mature in bone marrow?
True
What is the cloacal bursa of birds?
functionally the same to mammalian bone marrow for B cell differentiation
Where is the thymus located?
medastinium, cranial to heart
What is the thymic cortex?
stains darker than medlla
greater number of lympocytes present
area of positive selection
macrophages
What is the thymic medulla?
contains epithelial reticular cells
negative selection
form Hassals corpuscles
What are Hassals corpuscles?
large central calcified cells surrounded by circles of keratinized cells