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Microanatomy > Blood and Hematopoiesis > Flashcards

Blood and Hematopoiesis Flashcards

1
Q

What is BRU-E?

A

burst-forming unit, erythroid

precursor

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2
Q

What is whole blood and what are its functions?

A

specialized connective tissue
transport water, solutes and formed elements
temperature regulation
water balance

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3
Q

What is whole blood comprised of?

A

60% plasma

40% formed elements

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4
Q

What is plasma made up of?

A

90% water
8& proteins
2% other solutes

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5
Q

What are the two plasma proteins?

A

albumin and globulins

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6
Q

What are plasma electrolytes?

A

sodium, chloride and potassium

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7
Q

Whats the difference between plasma and serum?

A
  • plasma found in vasculture, serum in coagulation proteins

- plasma blood does not clot in seperaters, serum is allowed

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8
Q

What are formed elements?

A

erythrocytes, leukocytes and platelets

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9
Q

T or F: CBC varies in numbers and morphology in relation to disease processes in patients

A

True

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10
Q

What is the most numerous formed element in the blood?

A

RBC

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11
Q

T or F: RBC size varies in species?

A

True

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12
Q

How many days does a RBC survive in a dog?

A

110 days

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13
Q

How many days does a RBC survive in a horse?

A

160 days

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14
Q

How many days does a RBC survive in a feline?

A

70 days

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15
Q

How many days does a RBC survive in a bovine?

A

145 days

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16
Q

What shape are goat RBC?

A

spherical and irregular

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17
Q

What shape are camel RBC?

A

flat, thin

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18
Q

T or F: birds have nucleated RBCS, WBC and thrombocytes?

A

True

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19
Q

What are polychromatophils?

A

RBC’s that are 1 stage back in development
larger than mature RBC, smaller than neutrophil
lavender to purple color

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20
Q

T or F: finding a nucleated RBC is abnormal?

A

True

diseases affecting RBC formation

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21
Q

What is the least numerous formed element in the blood?

A

leukocytes

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22
Q

What is the function of leukocytes?

A

inflammation and immune response

23
Q

What are the two major categories of leukocytes?

A

myeloid (neutrophils, basophils, etc.)

lymphoid ( lymphocytes)

24
Q

What are the most numerous WBC’s?

A

neutrophils

25
Q

What is the function of neutrophils?

A

innate immunity

phagocytic and killing cells

26
Q

How can you identify hetrophils on a slide?

A

dynamic, dense granules

27
Q

What is a band neutrophil?

A

rare bands found in blood smears

one stage less mature than segmented neutrophil

28
Q

T or F: monocytes differentiate in macrophages in tissue?

A

True

29
Q

What are the functions of monocytes?

A

phagocytosis
iron storage and recycling
antigen presentation to T-lymphocytes

30
Q

What is the mononuclear phagocytic system comprised of?

A

circulating monocytes

tissue macrophages

31
Q

T or F: monocytes vary in morphology?

A

True

32
Q

T or FL monocytes are the largest cells on blood smears typically?

A

True

33
Q

T or F: Monocyte cytoplasms are frequently vacuolated ?

A

True

34
Q

T or F: it is normal to have low numbers of eosinophils in blood?

A

True

35
Q

What is the function of eosinophils?

A

modulate delayed and immediate type hypersensitivity reactions commonly associated with mast cells

36
Q

T or F: eosinophils defend against helminthic parasites?

A

True

37
Q

What does an eosinophil look like on morphology?

A

bright reddish-orange
eosinophillic granules
purple nucleus

38
Q

What is the least numerous WBC in blood?

A

basophils

39
Q

T or F: Heartworm disease is associated with basophils?

A

True

40
Q

What is the morphology of a basophil?

A

lavender granules

41
Q

What is the second most numerous cell population in the blood?

A

lymphocytes

42
Q

What is the function of lymphocytes?

A

humoral immunity: b-cells and plasma cells

cell mediated immunity: T cells

43
Q

What are subpopulations of lymphocytes?

A

small
large granular
reactive
plasma cells

44
Q

T or F: large granular lymphocytes are found in low numbers in sick animals?

A

False, HEALTHY animals

45
Q

What is the second most numerous formed element in the blood?

A

platelets

thrombocytes

46
Q

What are the functions of platelets?

A

clotting

primary inflammatory response

47
Q

What are the two types of bone marrow?

A

red marrow and yellow marrow

48
Q

What are the components of bone marrow?

A

sinusoids
stromal cells
stem cells and precursor cells
macrophages

49
Q

What is stoma of bone marrow?

A

connective tissue framework
composed of reticular cells& fibers and mesenchymal cells
support structure of bone marrow

50
Q

What are the cells of bone marrow?

A

hematopoietic stem cells

51
Q

What is hematopoiesis?

A

process of formed elements

52
Q

What is the process of RBC formation?

A 
Rubriblast
Prorubicyte
Rubricyte
Metarubricyte
Polychromatophllic RBC
Mature RBC
53
Q

What is the process of neutrophil formation?

A 
Myeloblast
Promyelocyte
Myelocyte
Metamyelocyte
Band neutrophil
Segmented neutrophil

Microanatomy (7 decks)

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