lymph node ( anatomy) Flashcards
what are the two routes lymphocytes enter lymph node?
afferent lymphatic vessels (10%)
HEVS in deep cortex by process called diapedesis (90%0
how many efferent vessels does each node have?
one
lymph circulation in lymph node
afferent –> subcapsular sinus –> trabecular sinus –> deep cortex –> medullary sinus –> leave node by efferent vessel
HEV have what?
aquaporin 1
sub scapular sinus + superficial cortex and trabecular are all made of what?
dense CT
storm of lymph node is made of what?
reticular fibers and cells
what cells are found in the germinal center?
reticular cells = secrete collagen
follicular dendritic cells
B lymphocytes
right upper quadrant drains into
right lymphatic duct
rest of body drains into
thoracic duct
venous angles between what two veins?
internal jugular and subclavian
whats the first line of defense?
diffuse lymphatic tissue
where is diffuse lymphatic tissue found
mucous membranes
git
respiratory tract
geniturinary tract
what cells does the mucosa / lamina propria contain?
lymphocytes
fibroblasts
eosinophils
plasma cells
palatine tonsils are covered by
stratified squamous nonkeratinized epithelium
tonsilar crypts are remnants of what?
2nd pharyngeal pouch
peyers patches
aggregated lymphatic nodules found in the ileum
t lymphocytes are mainly found in the
deep cortex but a little found in superificicial around germinal centers
b lymphocytes are found in the
germinal centers in the superficial cortex
CD3
T cell marker
CD20
B cell marker
reticular cells synthesize
type iii collagen and grout substance
dendritic cells
APCs
found with t lymphocytes = deep cortex
high level of MHC II
derived from bm
