HLA and Antigen presentation

Question 1

antigens

Answer 1

molecules that induce immune response

Question 2

epitope

Answer 2

part of Ag

Question 3

mhc aka

Answer 3

major histocompatibility complex

Question 4

what is mhc

Answer 4

part of multiple loci coding for molecules that reject grafts and play role in signaling between lymphocytes and APC

Question 5

hla job

Answer 5

present ags to T cells

Question 6

class I mhc

Answer 6

hla a b c

Question 7

class ii mhc

Answer 7

hla dp dq dr

Question 8

class iii

Answer 8

non histocompatibility genes

Question 9

how are hla classes organized on chromosome

Answer 9

ii –> iii –> i

Question 10

where can we find class I ?

Answer 10

almost all nucleated cells

Question 11

where can we find class ii?

Answer 11

APCs

Question 12

what cells don’t have mhc class I ?

Answer 12

brain placenta sperm RBCs

Question 13

hla class I and ii structure

Answer 13

I = I pp alpha
ii = 2 pp alpha and beta

Question 14

if exogenous ag then …

Answer 14

class ii

Question 15

if endogenous ag then …

Answer 15

class I

Question 16

if endogenous ag class I that means what cell involved?

Answer 16

T cytotoxic

Question 17

If exogenous ag class ii that means what cell is involved?

Answer 17

t helper

Question 18

Th express

Answer 18

cd4

Question 19

Tc express

Answer 19

cd8

Question 20

CD indicates what about the cell?

Answer 20

its function