LUTS, nocturia Flashcards
nocturia
definition
.
polyuria
definition
.
nocturia index
nocturnal polyuria index
definitions
.
what is ADH
aquaporins
Tea time Lasix in nocturia
efficacy
mean reduction 0.5
reduction of at least 1 episode 37%
NUCV reduces 18%
nocturia
a blocker efficacy
similar to Lasix
Veterans study
nocturia
anti cholinergics efficacy
reduction < 0.5
MA
what is DDAVP and its efficacy
V2
CI to DDAVP
.
SE OF DDAVP
.
what is BPH
Cunha
How common is BPH in autopsy series?
88% in 80s
How common is BPH in Asian men?
60s 40%
What is IPSS?
7 symptoms (0 - 35) 1 QoL
How many patients have BOO when Qmax < 10
How many Qmax < 10 have BOO
70% (ICS-BPH study)
53%
what is intravesical prostatic protrusion and cutoff?
150 - 250ml
PPV 94%
Natural hx of BPH
VA / OCS / MTOPS
.
Forms of clinical progression
MTOPS
Predictors of BPH progression
.
Relationship between LUTS and vascular diseases
Study = ?
MSAM-7
Physiology of UUO and BUO
Timing
Molecules involved
0 - 90min (PGE2, NO)
90min - 5h
> 5h (TXA2)
Time for recovery after obstruction
Tubular fx
Glomerular fx
14d
3m
WW for LUTS
Components =?
Efficacy =?
CONDUCT: IPSS 5 - 6
a-blocker in BPH:
Efficacy
IPSS 4
Qmax 3
ALLHAT study
Risk of combined CVD events : ___
Risk of CHF: ___
Risks of all-cause mortality: ___
25%
2X
NO
5ARI for BPH : Efficacy:
IPSS
Qmax
IPSS 5 - 6
Qmax 2
what is PLESS?
RRR 55% for AUR / BPH OT
SE of 5ARI Redcued libido: _ ED: _ Depression: _ Gynecomastia: _
6%
8%
10% higher
1%
MTOPS results IPSS: _ Qmax: _ AUR: _ OT: _ Clinical progression: _
7 4 81% 67% 66%
Efficacy of PDE5i on BPH
IPSS 3 , IIEF
McVary
Prostamol component and efficacy
Saw palmetto
Qmax
HoLEP
Fiber size
Energy setting
550um
2J 50Hz
HoLEP
Transfusion rate
Re-op rate
- 8%
0. 7% at 10y
Mechanism of PVP
YAG, LBO
600um , side-firing
oxy-Hb
poor absorption by water
what is the power of MoXy fiber?
180W
UK-ROPE study for PAE: results
IPSS
Re-tx
10 points at 12m
5% at 1y, overall 20%
Components of Urolift
3
Rezum:
Each __second treatment delivers __ml water vapour
9s
0.42ml
what is Memokath
nickel-titanium alloy
what is iTIND?
nitinol; butterfly-like
what is TUR syndrome
5
Glycine 1.5%
Osmolality: _
Absorption rate: _
200mOsm/L
20ml/min