Lupus - Ix

Question 1

Which bloods must be taken?

Answer 1

1. Inflammatory markers
2. FBC
3. Antibody serology

Question 2

Results of FBC in Lupus?

Answer 2

1. autoimmune haemolytics anaemia
2. Thrombocytopenia
3. Leukopenia

Question 3

Results of inflammatory markers in Lupus?

Answer 3

1. ESR is elevated

2. CRP is normal * key*

Question 4

Name 2 key antibodies in Lupus?

Answer 4

1. Anti-dsDNA
   - positive in 70%
   - correlated with disease activity
   - assoc with lupus nephritis
2. Anti-Sm antibody
   - highley specific for SLE

Question 5

Result of urinalysis in SLE?

Answer 5

1. Proteinuria

2. Casts