Gout - clinical feature Flashcards

1
Q

What is Gout?

A
  1. a form of microcrystal synovitis

2. caused by deposition of monosodium urate monohydrate in synovium

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2
Q

What is the main cause of Gout?

A

Hyperuricaemia

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3
Q

RF : factors decreasing excretion of uric acid?

A
  1. drugs - diuretics
  2. CKD
  3. Diabetic ketoacidosis
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4
Q

RF : factors increasing uric acid production?

A
  1. High alcohol consumption and obesity
  2. Psoriasis
  3. Increased cell turnover - myeloprolif disorders / haemolytic anaemia
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5
Q

3 major symptoms of ‘acute gout’?

A
  1. Pain
  2. Swelling
  3. Erythema

70% of cases - big toe is affected

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6
Q

Complications of gout

A
  1. Repeated acute attacks can cause chronic joint problems

2. Uric nephropathy

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