Gout - Mx

Question 1

First line : Acute mx of Gout

Answer 1

1. NSAIDS

e. g. Indomethicin / Naproxen

Question 2

Second line : Acute mx of Gout

Answer 2

1. Colchine

2. if not tolerant to NSAID e.g. CKD / GI ulcers

Question 3

Third line : Acute mx of Gout

Answer 3

1. Prednisolone ( if no response to prior)

Question 4

Chronic Gout - General management measures

Answer 4

1. Weightloss
2. Purine restricted diet
3. Reduce alcohol consumption

Question 5

When is medical tx indicated for Chronic Gout?

Answer 5

> 2 acute attacks of gout a year

Question 6

First line : Chronic mx of Gout

Answer 6

Xanthine oxidase inhibitor - Allopurinol

Question 7

Mechanism of xanthine oxidase inhibitor?

Answer 7

inhibit the enzyme which breaks down xanthine into uric acid