Luo Antibody-1-Structure

Question 1

vertebrate immune system specificity is capable of _______

Can discern between ________________

Answer 1

distinguishing between self and non-self

Small differences in non self(e.g. amino acid sequences)

Question 2

Types of vertebrate immune system memory

Answer 2

Acquired immune system memory

Immunization

Question 3

Immunity is brought about by __________
Which are generated in __________ from _________
And include _______ which mature in the _______, and ________ which mature in the ______

Answer 3

• A variety of leukocytes
• bone marrow
• undifferentiated stem cells
• T cells
• Thymus
• B cells
• Bone marrow

Question 4

Hemopoetic/Hematopoietic stem cells make

Answer 4

all types of white blood cells

Question 5

Thymus

Answer 5

a lymphoid gland in the chest

Question 6

bursa of fabricus

Answer 6

a bird-only organ involved in B-cell maturation

Question 7

An antigen is

Answer 7

any molecule that elicits an immune response

Question 8

Immune response involves two \_\_\_\_\_\_\_\_
Which are \_\_\_\_\_\_\_\_\_ and \_\_\_\_\_\_\_\_
Antibodies are at the heart of \_\_\_\_\_\_\_\_
     - they make up 20% of \_\_\_\_\_\_\_
     - and are produce by \_\_\_\_\_\_\_

Answer 8

complementary systems
humoral(fluid) and cellular
the humoral arm of this system
      - all blood protein
      - b cells

Question 9

Antibodies are __________

And their targets are ______

Answer 9

• Y-shaped proteins that bind specifically and very tightly to their targets
• antigens

Question 10

Antibody chains are linked via ___________________

Answer 10

non-covalent and covalent disulfide bonds

Question 11

An antibody can be digested by _____ to _________ fragments and _________ fragment

Answer 11

• papain
• 2 Fab (Fragment antigen binding fragments)
• 1 Fc fragment