Lung volumes and Alveolar Ventilation Flashcards

1
Q

What is Tidal Volume (VT)

A

Air inhaled and exhaled in normal respiration (~500ml)

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2
Q

What is the typical respiratory frequency?

A

~15 breaths/min

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3
Q

What is total ventilation (VE)?

A

Tidal volume x respiratory frequency

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4
Q

What does Tidal volume minus anatomic dead space equal to?

A

Amount of fresh air in alveoli

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5
Q

How do you calculate alveolar ventilation?

A

fresh air X respiratory frequency

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6
Q

What is spirometry?

A

Measurement of lung volumes and flow

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7
Q

What are the 3 different spirometers?

A

Volume displacement spirometers
Gas flow measurement devices
Peak Flow meters

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8
Q

What is the residual volume (RV)?

A

Volume of air that remains after forceful expiration

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9
Q

What is functional residual capacity (FRC)?

A

Amount of air remaining in the lungs after normal tidal expiration

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10
Q

What is total lung capacity (TLC)?

A

Maximum amount of air lungs can contain (RV X VC)

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11
Q

How are TLC, FRC and RV measured?

A

Gas dilution technique and body plethysmograph

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12
Q

What 5 things are pulmonary function tests used for?

A

Provide info on lung function
Assist with diagnosis of physiological abnormalities
Asses response to treatment
Determine fitness for surgical procedures

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13
Q

What is anatomical dead space (VD)?

A

Volume of air that does not take place in gas exchange

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14
Q

What is physiological dead space?

A

Sum of anatomical dead space plus alveolar dead space

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15
Q

What is alveolar dead space?

A

Areas of diseased tissue where gas exchange no longer occurs)

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16
Q

How do you calculate Alveolar ventilation?

A

VA = (VT - VD) X F

17
Q

What is the Alveolar gas equation?

A

PAO2 = FiO2 X (Patm - PH2O) - PaCO2/R
where Fi = 0.21
R = 0.8 as one oxygen molecule produces 0.8 carbon dioxide molecule
PACO2 = PaCO2

18
Q

What is Bohr’s equation?

A

VD/VT = (PACO2 - PECO2)/PACO2
PECO2 = partial pressure of expired CO2

19
Q

What is the normal ratio of dead space to tidal volume?

A

0.2 to 0.35 during resting breathing