Lung Funtction Tests And Common Lung Conditions Flashcards
What are obstructive lung diseases?
Obstruction of air flow, especially on expiration
Examples of obstructive lung disorders?
- Asthma
- COPD (chronic obstructive pulmonary disease)
• Chronic bronchitis – inflammation of the bronchi
• Emphysema – destruction of the alveoli + loss of elasticity
What are restrictive lung diseases?
Restriction of lung expansion, loss of lung compliance
Examples of restrictive lung diseases
o Fibrosis
- Formation of excess fibrous connective tissue – “stiff” lung
- Idiopathic (unknown cause)
- Asbestosis (and other occupational origins)
o Infant respiratory distress syndrome (insufficient surfactant production)
- Less willing to expand
o Oedema
- Fluid around alveoli creates pressure which resists inflation of alveoli
o Pneumothorax
- Air in pleural cavity pushing apart the pleurital membrane from the visceral membrane
- Lung now independent from chest wall and diaphragm and will no longer expand
What is spirometry?
Technique to measure lung function
Measurements are static or dynamic:
- Static – only consideration made is volume exhaled
- Dynamic – time taken to exhale a certain volume measured
(Can only measure volumes you expire e.g. NOT total lung capacity)
What is FEV1/FVC ratio?
- Forced expiratory volume in 1 second (FEV1)
o Fit, healthy, young adult males: 4.0L - Forced vital capacity (FVC) – total amount of air you can expire
o Fit, healthy young adult males: 5.0L - FEV/FVC = 80%
Spirometry in obstructive disease, what happens to FEV1/FVC?
- Big reduction in FEV1
- Rate of air expired is much slower – increase in resistance in airways or loss of elastic recoil in alveoli
- Total expired volume (FVC) reduced as less air is able to get out
Therefore ratio reduced
Spirometry in restrictive disease, what happens to FEV1/FVC?
- FEV1 decreases
- Only because there is less air in the lungs anyway
- Rate of air flow is not impeded in restrictive lung diseases
- Total amount of air expired is restricted as less air in lungs in first place
Ratio is unchanged