Lung development SMFM questions Flashcards
1
Q
At 16-26 weeks what is happening in lung development
A
bronchioles
Acinar saccules
Thinning of capillary epitheial space
Differentiation of type1 and type2 pneumocytes
2
Q
At 32 weeks + what is happening in lung development
A
septation of alveoli
maturation of type 2 and surfactant production
macrophages are also involved in surfactant metabolisum
3
Q
what are the substrates for surfactant
A
glucose, phosphate, fatty acids
4
Q
What is the major phospholipid in surfactant
A
phosphatidylcholine is remodeled to yield a phosphatidylcholine with palmitic acids in the 1-acyl and 2-acyl positions, referred to as saturated phosphatidylcholine.
