lqc 5b exam qs

Question 1

what is the name of the antigen-presenting cell involved in the activation of T killer cells.

Answer 1

virus infected host cell

Question 2

Explain the importance of mitosis in the proliferation of activated T killer cells.

Answer 2

to increase the number of T killer cells, so that T killer cells are antigen- specific, so that host- infected cells can be destroyed faster

Question 3

Explain how virus-infected host cells are destroyed by T killer cells.

Answer 3

release of chemicals from T killer cells, enzymes cause the lysis of host infected cells

Question 4

Describe the role of macrophages in the activation of T killer cells.

Answer 4

macrophages present antigen to T helper cells, binding to CD4 antigen on T helper cells, T helper cells are needed to activate T killer cells

Question 5

Describe the role of macrophages in the destruction of viruses.

Answer 5

phagocytosis of virus, destruction of virus with enzymes, enzymes breakdown protein coat

Question 6

Explain how cyclosporin will prevent the destruction of the transplanted organ

Answer 6

T helper cells are needed to activate T killer cells, T killer cells activated by cytokines, there will not be any T killer cells to release enzymes, cells of the transplant will not be destroyed by the enzymes