barriers- lqc 3b Flashcards
skin
Contains the tough protein keratin, however the skin can be breached by wounds. Blood clotting helps prevent this. Skin flora outcompetes and prevents colonisation by other bacteria.
mucosal membranes
Line the airways and gut. The mucus traps microbes and other particles. Beating cilia carry the mucus up to the throat to be swallowed. Secretions from eyes & nose contain the enzyme lysozyme that breaks down bacterial cell walls causing them to burst.
stomach acid
Contains hydrochloric acid, giving a pH of less than 2.0. This kills most bacteria that enter with food or drink. This is also the optimum pH for the digestive enzyme pepsin.
gut flora
‘Friendly’ bacteria found in both intestines. We have a mutualistic relationship with them. They aid digestion and outcompete pathogenic bacteria for food and space. The bacteria also secrete chemicals (lactic acid) to aid the defence against pathogens