lqc 5a exam qs

Question 1

Steroids reduce inflammation. Explain why reducing inflammation could help to reduce a patient’s immune response.

Answer 1

there will not be such an increase in flow of blood, there will not be such an increase in white blood cells to the area, fewer macrophages to present antigen for T helper cells, without T helper cells activation B cells will not be activated

Question 2

Azathioprine blocks DNA replication. Explain how azathioprine affects the number of T helper cells.

Answer 2

azothioprine will prevent the increase in T helper cells, as they will not be able to divide, they will not be able to replicate the dna needed for mitosis takes place

Question 3

Explain why there is a delay, following this infection, before the number of virus particles increases.

Answer 3

synthesis of viral components, assembly of virus

Question 4

Explain why there is a delay before the level of antibodies starts to rise.

Answer 4

B cell response, antigen has to attach to B cells, T helper cells are needed in activation of B cells, T helper cells have to be activated before they can activate B cells, cloning of B cells has to take place, B cells differentiate into plasma cells, antibody production by plasma cells