Lower GI Conditions Flashcards
What is constipation?
Difficulty in passing stools or an inability to pass stools
How can constipation present?
Straining
Lumpy/Hard stools
Feeling of incomplete evacuation
Fewer than 3 bowel movements a week
What are some causes of constipation?
Normal transit constipation
Slow colonic transport
Defecation problems
What is the treatment for constipation?
Psychological support Increased fluid intake Increased activity Increased dietary fibre Fibre medication Laxitives
What is diarrhoea?
A symptom that occurs in many conditions. Presents as loose/watery stools passed more than 3 times a day
What causes diarrhoea?
An unwanted substance triggers gut motility and secretions to remove it, increasing water in the bowel
What are the 2 broad causes of diarrhoea?
Secretory causes
Osmotic causes
What are secretory causes of diarrhoea?
Excess ion secretion gives excess Cl- or HCO3- in the bowel
What are osmotic causes of diarrhoea?
Gut lumen contains too much osmotic material
What is the appendix?
Diverticula off the caecum
Which artery supplies the appendix?
Ileocolic branch of Superior Mesenteric
How can appendicitis present?
Acute
Gangrenous
How does acute appendicitis present?
Mucosal Oedema
How does gangrenous appendicitis present?
Transmural inflammation and necrosis
How can the causes of appendicitis be classified?
Classic
Alternative
What happens in classic appendicitis?
The lumen of the appendix becomes blocked, increasing intraluminal pressure.
Venous pressure rises giving oedema, reducing arterial supply to the appendix causing ischaemia
What happens in alternative appendicitis?
A viral/bacterial infection causes mucosal changes that allow for bacterial invasion of the appendiceal wall
How does appendicitis manifest?
Poorly-localised peri-umbilical pain that moves to the R iliac fossa after 12-24h
Anorexia
Nausea and Vomiting
Low Grade fever
Why can the pain for appendicitis be felt in areas other than the RIF?
The position of the appendix varies slightly
Which position can the appendix be found in?
Retrocoecal Subcoecal Pelvic Pre-ileal Post-ileal
What are some signs of appendicitis?
Patient appears ill Fever/Tachycardia Lie still due to inflamed peritoneum Localised R quadrant tenderness Reboud tenderness in RIF Pain localised to McBurney's Point
Where is McBurney’s Point?
2/3 of the way from Umbilicus to ASIS
How is the diagnosis of appendicitis confirmed?
History/exam is often enough
Bloods - Raised CRP/WCC
What needs to be excluded with possible appendicitis cases?
Ectopic pregnancy
What is the treatment for appendicitis?
Open appendicectomy
Laprascopic Appendicectomy
What is Diverticulosis?
Outpouchings of the mucosa and submucosa that herniate through the muscularis layers
Where is Diverticulosis common?
Colon, commonly sigmoid
What is thought to cause Diverticulosis?
Low fibre diet giving hard/bulky stool that needs more effort to pass
What is Acute Diverticulitis?
Diverticulae become inflamed/perforate.
The entrance to the diverticula is occluded by faeces giving inflammation
How can acute diverticulitis present?
Uncomplicated
Complicated
What is uncomplicated diverticulitis?
Diverticulitis with inflammation and small abscesses
What is complicated diverticulitis?
Diverticulitis with larger abcess formation
What are some symptoms of diverticulitis?
Abdo pain at sight of inflammation, usually lower left quadrant Fever Bloating Constipation Haematochezia Fresh PR bleed
What are some signs of diverticulitis?
Localised abdominal tenderness
Distension
Reduced bowel sounds
Signs of Peritonitis
What tests are appropriate in diverticulitis?
Bloods - WCC/CRP
USS
CT
Colonoscopy
What is the treatment of diverticulitis?
Antibiotics
Fluid resus
Analgesia
Surgical intervention if perforated
What is Acute Mesenteric Ischaemia?
The sudden decrease in blood supply to the bowel, leading to bowel ischaemia, gangrene and death
What are some causes of acute mesenteric ischaemia?
Thrombus in Situ
Embolism
Non-occlusive cause
Venous occlusion/congestion
What are some risk factors for acute mesenteric ischaemia?
Hypertension
Hyperlipidaemia
Smoking
Af
What are clinical features of acute mesenteric ischaemia?
Generalised abdominal pain
Diffuse, constant
Nausea and Vomiting
What will examination demonstrate in acute mesenteric ischaemia?
Often nothing
What are some differentials with acute mesenteric ischaemia?
Peptic Ulcer Disease
Bowel Obstruction
AAA
Which investigations are appropriate for acute mesenteric ischaemia?
ABG - ?Acidosis/Lactate
FBC, U+E,LFTs
Which investigation is definitive with acute mesenteric ischaemia?
CT Abdo/Pelvis with Contrast
What is the management for acute mesenteric ischaemia?
Surgical intervention
Excision of the Necrotic Bowel
Revascularisation of the bowel
What is Crohn’s Disease?
A form of inflammatory bowel disease