HPB Flashcards
What is Bile formed from?
Cholesterol, Phospholipids and Bile pigments
Where is bile stored?
Gallbladder
Why do Gallstones form?
Due to a supersaturation of bile
What are the different types of gallstone?
Cholesterol Stones
Pigment Stones
Mixed Stones
How are Cholesterol stones formed?
Formed from excess cholesterol, linked to poor diet and obesity
How are Pigment stones formed?
Formed from bile pigments due to an excess pigment production
What are Mixed gallstones formed of?
A mixture of Cholesterol and Bile pigments
What are some risk factors for Gallstone disease?
The 5 Fs Pregnancy Oral contraceptives Haemolytic anaemia Malabsorption conditions
What are the 5 Fs in relation to gallstones?
Fat Female Fertile Fourty Family Hx
What is Biliary colic?
Condition when the gallbladder neck becomes impacted with a gallstone. There are no features of inflammation, however can have pain due to contraction of the neck against the stone
How is the pain often described in biliary colic?
Sudden
Dull
Colicky
Where is the pain felt in biliary colic?
RUQ
Can radiate to Epigastrium +/- Back
What can often trigger biliary colic?
Consumption of fatty foods
What are the management options for biliary colic?
Analgesia - Paracetamol +/- NSAIDs. Opioids if needed
Lifestyle modifications
Surgery
When should a Laparoscopic Cholecystectomy be offered with biliary colic?
Within 6/52 of initial presentation, due to risk of recurrence/complications